Development of the Myocardial Contractile System

Overview

Journal Experientia

Specialty Science

Date 1988 Dec 1

PMID 3058500

Citations 11

Authors

T Nakanishi

M Seguchi

A TAKAO

Affiliations

Soon will be listed here.

Abstract

Recent studies regarding developmental changes in the myocardial contractile system from fetal, newborn, and adult animals are reviewed. From the data obtained so far, we conclude that in the early fetus myocardial contraction is mainly dependent on Ca which enters via the sarcolemma. Ca release from the sarcoplasmic reticulum is minimal. The role of the sarcoplasmic reticulum as a source of contractile Ca increases and the role of Ca influx across the sarcolemma in contractile system decreases with development.

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