Astrocytes and Microglia: Models and Tools

Overview

Journal J Exp Med

Specialties Allergy & Immunology
General Medicine

Date 2018 Dec 14

PMID 30541903

Citations 64

Authors

Kevin A Guttenplan

Shane A Liddelow

Affiliations

Soon will be listed here.

Abstract

Glial cells serve as fundamental regulators of the central nervous system in development, homeostasis, and disease. Discoveries into the function of these cells have fueled excitement in glial research, with enthusiastic researchers addressing fundamental questions about glial biology and producing new scientific tools for the community. Here, we outline the pros and cons of in vivo and in vitro techniques to study astrocytes and microglia with the goal of helping researchers quickly identify the best approach for a given research question in the context of glial biology. It is truly a great time to be a glial biologist.

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