Astrocytes "Chordinate" Synapse Maturation and Plasticity

Overview

Journal Neuron

Publisher Cell Press

Specialty Neurology

Date 2018 Dec 7

PMID 30521771

Citations 4

Authors

Katherine T Baldwin

Cagla Eroglu

Affiliations

Soon will be listed here.

Abstract

A key step in excitatory synapse maturation is the switch in AMPA receptor subunit composition to GluA2-containing calcium-impermeable receptors. Now, Blanco-Suarez et al. (2018) demonstrate that astrocyte-secreted chordin-like 1 drives this process, enabling synapse maturation and limiting plasticity.

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