Big Bottlenecks in Cardiovascular Tissue Engineering

Overview

Journal Commun Biol

Specialty Biology

Date 2018 Nov 28

PMID 30480100

Citations 41

Authors

Ngan F Huang

Vahid Serpooshan

Viola B Morris

Nazish Sayed

Gaspard Pardon

Oscar J Abilez

Karina H Nakayama

Beth L Pruitt

Sean M Wu

Young-Sup Yoon

Jianyi Zhang

Joseph C Wu

Affiliations

Soon will be listed here.

Abstract

Although tissue engineering using human-induced pluripotent stem cells is a promising approach for treatment of cardiovascular diseases, some limiting factors include the survival, electrical integration, maturity, scalability, and immune response of three-dimensional (3D) engineered tissues. Here we discuss these important roadblocks facing the tissue engineering field and suggest potential approaches to overcome these challenges.

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A Review on the Applications of Natural Biodegradable Nano Polymers in Cardiac Tissue Engineering.

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