A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV

Overview

Journal AIDS Behav

Specialty Infectious Diseases

Date 2018 Nov 17

PMID 30443806

Citations 31

Authors

Jennifer A Pellowski

Devon M Price

Abigail D Harrison

Emily L Tuthill

Landon Myer

Don Operario

Mark N Lurie

Affiliations

Soon will be listed here.

Abstract

A systematic review and meta-analysis was conducted to determine the efficacy of women-focused ART adherence interventions. Included studies (a) reported on a behavioral ART adherence intervention for cis-women living with HIV, (b) measured ART adherence as an outcome, and (c) employed a randomized controlled trial design. Thirteen studies were included in the meta-analysis. Overall, interventions significantly improved ART adherence compared to control conditions (random-effects d = 0.82, 95% CI [0.18, 1.45], p = 0.01), however, this was largely driven by two studies that had effect sizes greater than 3 standard errors above the mean effect size. Key moderators were location, recruitment method, group-based intervention, and alteration of the healthcare system. Innovative behavioral interventions that focus on young women and adolescents, target the critical periods of pregnancy and postpartum and test the integration of multiple levels of intervention to create lasting effects on ART adherence are needed.

Citing Articles

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Social Location and Decision-Making Among Women Living with HIV in the Southern United States: An Intersectional Approach.

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