» Articles » PMID: 30424079

Optofluidics in Microstructured Optical Fibers

Overview
Publisher MDPI
Date 2018 Nov 15
PMID 30424079
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

In this paper, we review the development and applications of optofluidics investigated based on the platform of microstructured optical fibers (MOFs) that have miniature air channels along the light propagating direction. The flexibility of the customizable air channels of MOFs provides enough space to implement light-matter interaction, as fluids and light can be guided simultaneously along a single strand of fiber. Different techniques employed to achieve the fluidic inlet/outlet as well as different applications for biochemical analysis are presented. This kind of miniature platform based on MOFs is easy to fabricate, free of lithography, and only needs a tiny volume of the sample. Compared to optofluidics on the chip, no additional waveguide is necessary to guide the light since the core is already designed in MOFs. The measurements of flow rate, refractive index of the filled fluids, and chemical reactions can be carried out based on this platform. Furthermore, it can also demonstrate some physical phenomena. Such devices show good potential and prospects for applications in bio-detection as well as material analysis.

Citing Articles

Self-assembled sub-picoliter liquid periodic structures in a hollow optical fiber.

An S, Jeong S, Hwang J, Jung Y, Kim J, Oh K Sci Rep. 2024; 14(1):26210.

PMID: 39482382 PMC: 11528097. DOI: 10.1038/s41598-024-75961-6.


Optofluidic Tweezers: Efficient and Versatile Micro/Nano-Manipulation Tools.

Zhu Y, You M, Shi Y, Huang H, Wei Z, He T Micromachines (Basel). 2023; 14(7).

PMID: 37512637 PMC: 10384111. DOI: 10.3390/mi14071326.


Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review.

Li B, Zhang R, Bi R, Olivo M Biosensors (Basel). 2023; 13(1).

PMID: 36671899 PMC: 9855469. DOI: 10.3390/bios13010064.


Towards Multiplexed and Multimodal Biosensor Platforms in Real-Time Monitoring of Metabolic Disorders.

Chu S, Nguyen H, Zhang J, Tabassum S, Cao H Sensors (Basel). 2022; 22(14).

PMID: 35890880 PMC: 9323394. DOI: 10.3390/s22145200.


Functionalized Microstructured Optical Fibers: Materials, Methods, Applications.

Ermatov T, Skibina J, Tuchin V, Gorin D Materials (Basel). 2020; 13(4).

PMID: 32092963 PMC: 7078627. DOI: 10.3390/ma13040921.


References
1.
Haeberle S, Zengerle R . Microfluidic platforms for lab-on-a-chip applications. Lab Chip. 2007; 7(9):1094-110. DOI: 10.1039/b706364b. View

2.
Motz J, Hunter M, Galindo L, Gardecki J, Kramer J, Dasari R . Optical fiber probe for biomedical Raman spectroscopy. Appl Opt. 2004; 43(3):542-54. DOI: 10.1364/ao.43.000542. View

3.
Lien V, Vollmer F . Microfluidic flow rate detection based on integrated optical fiber cantilever. Lab Chip. 2007; 7(10):1352-6. DOI: 10.1039/b706944h. View

4.
Cordeiro C, Franco M, Chesini G, Barretto E, Lwin R, Brito Cruz C . Microstructured-core optical fibre for evanescent sensing applications. Opt Express. 2009; 14(26):13056-66. DOI: 10.1364/oe.14.013056. View

5.
Warren-Smith S, Afshar S, Monro T . Theoretical study of liquid-immersed exposed-core microstructured optical fibers for sensing. Opt Express. 2008; 16(12):9034-45. DOI: 10.1364/oe.16.009034. View