Nationwide Use of Inhaled Corticosteroids by South Korean Asthma Patients: an Examination of the Health Insurance Review and Service Database

Overview

Journal J Thorac Dis

Publisher AME Publishing Company

Specialty Pulmonary Medicine

Date 2018 Nov 13

PMID 30416788

Citations 12

Authors

Joon Young Choi

Hyoung Kyu Yoon

Jae Ha Lee

Kwang Ha Yoo

Bo Yeon Kim

Hye Won Bae

Young Kyoon Kim

Chin Kook Rhee

Affiliations

Soon will be listed here.

Abstract

Background: Previous studies have found that the prescription rates of inhaled corticosteroid (ICS) were considerably low although it is recommended as the optimal asthma treatment. The aim of this study was to analyze the current status of ICS prescription for asthma patients in the South Korea.

Methods: We evaluated quality assessment data based on nationwide Health Insurance Review and Service (HIRA) database from July 2013 to June 2014. ICS prescription rates in asthma patients were analyzed by types and specialty of medical institutions. Also, we graded medical institutions by their ICS prescription rate. In addition, ICS prescription rates were calculated by patient gender, age, and insurance type.

Results: This study included 831,613 patients and 16,804 institutions in the analysis. The overall mean ICS prescription rate was 22.58%. Tertiary hospitals had the highest mean prescription rate (84.16%) whereas primary healthcare clinics had the lowest (20.71%). By specialty, internal medicine physicians prescribed ICS more frequently compared to other specialists. Of all, 47.17% of medical institutions prescribed ICS to <10% of asthma patients, while less than 6% of institutions prescribed ICS to >80% of asthma patients. Also, we found that female and patients with age >90 or <20 years exhibited lower ICS prescription rate.

Conclusions: The ICS prescription rate was found to be inadequate, given the importance of ICS as an asthma treatment. The prescription rates were especially low in primary healthcare clinics, and by specialists in fields other than internal medicine.

Citing Articles

Inhaled Corticosteroids and the Risk of Nontuberculous Mycobacterial Infection in Chronic Airway Disease: A Nationwide Population-Based Study.

Yoon E, Lee H, Yoon H Tuberc Respir Dis (Seoul). 2024; 87(4):473-482.

PMID: 38835294 PMC: 11468439. DOI: 10.4046/trd.2024.0038.

Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III.

Yoo K, Kim S, Kim S, Moon J, Park H, Chang Y Korean J Intern Med. 2023; 39(1):123-136.

PMID: 38057957 PMC: 10790050. DOI: 10.3904/kjim.2023.086.

Increasing the accuracy of the asthma diagnosis using an operational definition for asthma and a machine learning method.

Joo H, Lee D, Lee S, Kim Y, Rhee C BMC Pulm Med. 2023; 23(1):196.

PMID: 37280559 PMC: 10245465. DOI: 10.1186/s12890-023-02479-4.

Prescription Patterns of Asthma Preventers Among Children and Adolescents Between Australia and South Korea.

Seo M, Hillen J, Kang D, Pratt N, Shin J Front Pharmacol. 2022; 13:834116.

PMID: 35668949 PMC: 9163376. DOI: 10.3389/fphar.2022.834116.

Additive effects of coexisting respiratory comorbidities on overall or respiratory mortality in patients with asthma: a national cohort study.

Yeo Y, Lee H, Ryu J, Chung S, Park T, Park D Sci Rep. 2022; 12(1):8105.

PMID: 35577832 PMC: 9110422. DOI: 10.1038/s41598-022-12103-w.

References

Fanta C . Asthma. N Engl J Med. 2009; 360(10):1002-14. DOI: 10.1056/NEJMra0804579. View

Reddel H, Beckert L, Moran A, Ingham T, Ampon R, Peters M . Is higher population-level use of ICS/LABA combination associated with better asthma outcomes? Cross-sectional surveys of nationally representative populations in New Zealand and Australia. Respirology. 2017; 22(8):1570-1578. DOI: 10.1111/resp.13123. View

Park H, Byun M, Kim H, Ahn C, Rhee C, Kim K . Regular follow-up visits reduce the risk for asthma exacerbation requiring admission in Korean adults with asthma. Allergy Asthma Clin Immunol. 2018; 14:29. PMC: 6038276. DOI: 10.1186/s13223-018-0250-0. View

Akinbami L, Moorman J, Bailey C, Zahran H, King M, Johnson C . Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010. NCHS Data Brief. 2012; (94):1-8. View

McCracken J, Veeranki S, Ameredes B, Calhoun W . Diagnosis and Management of Asthma in Adults: A Review. JAMA. 2017; 318(3):279-290. DOI: 10.1001/jama.2017.8372. View

Boulet L, Turcotte H, Prince P, Lemiere C, Olivenstein R, Laprise C . Benefits of low-dose inhaled fluticasone on airway response and inflammation in mild asthma. Respir Med. 2009; 103(10):1554-63. DOI: 10.1016/j.rmed.2009.02.015. View

Ciprandi G, Schiavetti I, Ricciardolo F . The impact of aging on outpatients with asthma in a real-world setting. Respir Med. 2018; 136:58-64. DOI: 10.1016/j.rmed.2018.01.018. View

Baiardini I, Braido F, Bonini M, Compalati E, Canonica G . Why do doctors and patients not follow guidelines?. Curr Opin Allergy Clin Immunol. 2009; 9(3):228-33. DOI: 10.1097/ACI.0b013e32832b4651. View

Dominguez-Ortega J, Phillips-Angles E, Barranco P, Quirce S . Cost-effectiveness of asthma therapy: a comprehensive review. J Asthma. 2014; 52(6):529-37. DOI: 10.3109/02770903.2014.999283. View

10.

Reddel H, Busse W, Pedersen S, Tan W, Chen Y, Jorup C . Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study. Lancet. 2016; 389(10065):157-166. DOI: 10.1016/S0140-6736(16)31399-X. View

11.

Cazzoletti L, Marcon A, Janson C, Corsico A, Jarvis D, Pin I . Asthma control in Europe: a real-world evaluation based on an international population-based study. J Allergy Clin Immunol. 2007; 120(6):1360-7. DOI: 10.1016/j.jaci.2007.09.019. View

12.

Kynyk J, Mastronarde J, McCallister J . Asthma, the sex difference. Curr Opin Pulm Med. 2010; 17(1):6-11. DOI: 10.1097/MCP.0b013e3283410038. View

13.

Steppuhn H, Langen U, Mueters S, Dahm S, Knopf H, Keil T . Asthma management practices in adults--findings from the German Health Update (GEDA) 2010 and the German National Health Interview and Examination Survey (DEGS1) 2008-2011. J Asthma. 2015; 53(1):50-61. DOI: 10.3109/02770903.2015.1059853. View

14.

Masoli M, Fabian D, Holt S, Beasley R . The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy. 2004; 59(5):469-78. DOI: 10.1111/j.1398-9995.2004.00526.x. View

15.

Adams R, Fuhlbrigge A, Guilbert T, Lozano P, Martinez F . Inadequate use of asthma medication in the United States: results of the asthma in America national population survey. J Allergy Clin Immunol. 2002; 110(1):58-64. DOI: 10.1067/mai.2002.125489. View

16.

Laforest L, Belhassen M, Devouassoux G, Didier A, Ginoux M, Van Ganse E . Long-Term Inhaled Corticosteroid Adherence in Asthma Patients with Short-Term Adherence. J Allergy Clin Immunol Pract. 2016; 4(5):890-899.e2. DOI: 10.1016/j.jaip.2016.07.008. View

17.

Williams S, Wagner S, Kannan H, Bolge S . The association between asthma control and health care utilization, work productivity loss and health-related quality of life. J Occup Environ Med. 2009; 51(7):780-5. DOI: 10.1097/JOM.0b013e3181abb019. View

18.

Schatz M, Camargo Jr C . The relationship of sex to asthma prevalence, health care utilization, and medications in a large managed care organization. Ann Allergy Asthma Immunol. 2004; 91(6):553-8. DOI: 10.1016/S1081-1206(10)61533-5. View

19.

Adams N, Bestall J, Lasserson T, Jones P, Cates C . Fluticasone versus placebo for chronic asthma in adults and children. Cochrane Database Syst Rev. 2005; (4):CD003135. DOI: 10.1002/14651858.CD003135.pub3. View

20.

Bosnic-Anticevich S, Kritikos V, Carter V, Yan K, Armour C, Ryan D . Lack of asthma and rhinitis control in general practitioner-managed patients prescribed fixed-dose combination therapy in Australia. J Asthma. 2017; 55(6):684-694. DOI: 10.1080/02770903.2017.1353611. View