Microfluidic Autologous Serum Eye-Drops Preparation As a Potential Dry Eye Treatment

Overview

Journal Micromachines (Basel)

Publisher MDPI

Date 2018 Nov 9

PMID 30404287

Citations 1

Authors

Takao Yasui

Jumpei Morikawa

Noritada Kaji

Manabu Tokeshi

Kazuo Tsubota

Yoshinobu Baba

Affiliations

Soon will be listed here.

Abstract

Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide benefits for all dry eye patients; 100% and 90% removal efficiencies are achieved for 10 μm microbeads and whole human blood cells, respectively. Since our strategy allows researchers to integrate other functional microchannels into one device, such a microfluidic device will be able to offer a new one-step preparation system for autologous serum eye-drops.

Citing Articles

Micro/Nano Devices for Chemical Analysis.

Tokeshi M, Sato K Micromachines (Basel). 2018; 7(9).

PMID: 30404336 PMC: 6190470. DOI: 10.3390/mi7090164.

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