Stroke Management: An Emerging Role of Nanotechnology

Overview

Journal Micromachines (Basel)

Publisher MDPI

Date 2018 Nov 8

PMID 30400452

Citations 17

Authors

Deepaneeta Sarmah

Jackson Saraf

Harpreet Kaur

Kanta Pravalika

Rakesh Kumar Tekade

Anupom Borah

Kiran Kalia

Kunjan R Dave

Pallab Bhattacharya

Affiliations

Soon will be listed here.

Abstract

Stroke is among the leading causes of mortality and morbidity worldwide. Stroke incidences and associated mortality are expected to rise to 23 million and 7.8 million, respectively, by 2030. Further, the aging population, imbalanced lifestyles, and environmental factors continue to shift the rate of stroke incidence, particularly in developing countries. There is an urgent need to develop new therapeutic approaches for treating stroke. Nanotechnology is a growing field, offering an encouraging future prospect for medical research in the management of strokes. The world market for nanotechnology derived products is expected to rise manyfold in the coming decades. Different types of nanomaterials such as perfluorocarbon nanoparticles, iron oxide nanoparticles, gold nanoparticles, polymeric nanoparticles, quantum dots, nanospheres, etc. have been developed for the diagnosis as well as therapy of strokes. Today, nanotechnology has also been integrated with stem cell therapy for treating stroke. However several obstacles remain to be overcome when using such nanomaterials for treating stroke and other neurological diseases.

Citing Articles

Targeted pathophysiological treatment of ischemic stroke using nanoparticle-based drug delivery system.

Liu W, Liu L, Li H, Xie Y, Bai J, Guan J J Nanobiotechnology. 2024; 22(1):499.

PMID: 39164747 PMC: 11337765. DOI: 10.1186/s12951-024-02772-2.

Advances in Engineered Nanoparticles for the Treatment of Ischemic Stroke by Enhancing Angiogenesis.

Wang G, Li Z, Wang G, Sun Q, Lin P, Wang Q Int J Nanomedicine. 2024; 19:4377-4409.

PMID: 38774029 PMC: 11108071. DOI: 10.2147/IJN.S463333.

Surface-Tailored Nanoplatform for the Diagnosis and Management of Stroke: Current Strategies and Future Outlook.

Shah H, Paul G, Yadav A Mol Neurobiol. 2023; 61(3):1383-1403.

PMID: 37707740 DOI: 10.1007/s12035-023-03635-x.

Stimuli-Responsive Nanotherapeutics for Treatment and Diagnosis of Stroke.

Choudhary M, Chaudhari S, Gupta T, Kalyane D, Sirsat B, Kathar U Pharmaceutics. 2023; 15(4).

PMID: 37111522 PMC: 10141724. DOI: 10.3390/pharmaceutics15041036.

Recent Advances in Nanomaterials for Diagnosis, Treatments, and Neurorestoration in Ischemic Stroke.

Lin X, Li N, Tang H Front Cell Neurosci. 2022; 16:885190.

PMID: 35836741 PMC: 9274459. DOI: 10.3389/fncel.2022.885190.

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