Transcranial Magnetic Stimulation for Adolescent Depression

Overview

Journal Child Adolesc Psychiatr Clin N Am

Date 2018 Nov 4

PMID 30389074

Citations 20

Authors

Paul E Croarkin

Frank P MacMaster

Affiliations

Soon will be listed here.

Abstract

Adolescent depression is a substantial global public health problem that contributes to academic failure, occupational impairment, deficits in social functioning, substance use disorders, teen pregnancy, and completed suicide. Existing treatment options often have suboptimal results and uncertain safety profiles. Transcranial magnetic stimulation may be a promising, brain-based intervention for adolescents with depression. Existing work has methodological weaknesses, and larger, neurodevelopmentally informed studies are urgently needed. Treatment with transcranial magnetic stimulation may modulate cortical GABAergic and glutamatergic imbalances. Future study will inform dosing approaches for TMS based on GABAergic and glutamatergic biomarkers.

Citing Articles

Frontal Pole Neuromodulation for Impulsivity and Suicidality in Veterans With Mild Traumatic Brain Injury and Common Co-Occurring Mental Health Conditions: Protocol for a Pilot Randomized Controlled Trial.

Bernanke A, Hasley R, Sabetfakhri N, de Wit H, Smith B, Wang L JMIR Res Protoc. 2024; 13():e58206.

PMID: 39671573 PMC: 11681286. DOI: 10.2196/58206.

Knowledge, attitude, and practice of depression among university students.

Wang X, Li C Brain Behav. 2024; 14(9):e70030.

PMID: 39295097 PMC: 11410866. DOI: 10.1002/brb3.70030.

Cerebellar transcranial magnetic stimulation for improving balance capacity and activity of daily living in stroke patients: a systematic review and meta-analysis.

Wang J, Wu Z, Hong S, Ye H, Zhang Y, Lin Q BMC Neurol. 2024; 24(1):205.

PMID: 38879485 PMC: 11179288. DOI: 10.1186/s12883-024-03720-1.

Annual Research Review: Puberty and the development of anhedonia - considering childhood adversity and inflammation.

Gupta T, Eckstrand K, Forbes E J Child Psychol Psychiatry. 2024; 65(4):459-480.

PMID: 38391011 PMC: 10939801. DOI: 10.1111/jcpp.13955.

Il1r2 and Tnfrsf12a in transcranial magnetic stimulation effect of ischemic stroke via bioinformatics analysis.

Zhao M, Liu A, Wu J, Mo L, Lu F, Wan G Medicine (Baltimore). 2024; 103(4):e36109.

PMID: 38277520 PMC: 10817048. DOI: 10.1097/MD.0000000000036109.

References

Geddes L . Brain stimulation in children spurs hope - and concern. Nature. 2015; 525(7570):436-7. DOI: 10.1038/525436a. View

Yang X, Kirton A, Wilkes T, Pradhan S, Liu I, Jaworska N . Glutamate alterations associated with transcranial magnetic stimulation in youth depression: a case series. J ECT. 2014; 30(3):242-7. DOI: 10.1097/YCT.0000000000000094. View

Lisanby S . Noninvasive Brain Stimulation for Depression - The Devil Is in the Dosing. N Engl J Med. 2017; 376(26):2593-2594. DOI: 10.1056/NEJMe1702492. View

Krnjevic K, Randic M, Straughan D . Nature of a cortical inhibitory process. J Physiol. 1966; 184(1):49-77. PMC: 1357547. DOI: 10.1113/jphysiol.1966.sp007903. View

Rossi S, Hallett M, Rossini P, Pascual-Leone A . Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol. 2009; 120(12):2008-2039. PMC: 3260536. DOI: 10.1016/j.clinph.2009.08.016. View

Blumberger D, Vila-Rodriguez F, Thorpe K, Feffer K, Noda Y, Giacobbe P . Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial. Lancet. 2018; 391(10131):1683-1692. DOI: 10.1016/S0140-6736(18)30295-2. View

Grabb M, Gobburu J . Challenges in developing drugs for pediatric CNS disorders: A focus on psychopharmacology. Prog Neurobiol. 2016; 152:38-57. DOI: 10.1016/j.pneurobio.2016.05.003. View

Walter G, Tormos J, Israel J, Pascual-Leone A . Transcranial magnetic stimulation in young persons: a review of known cases. J Child Adolesc Psychopharmacol. 2001; 11(1):69-75. DOI: 10.1089/104454601750143483. View

Fontella F, Vendite D, Tabajara A, Porciuncula L, Torres I, Jardim F . Repeated restraint stress alters hippocampal glutamate uptake and release in the rat. Neurochem Res. 2004; 29(9):1703-9. DOI: 10.1023/b:nere.0000035805.46592.6c. View

10.

Walkup J . Antidepressant Efficacy for Depression in Children and Adolescents: Industry- and NIMH-Funded Studies. Am J Psychiatry. 2017; 174(5):430-437. DOI: 10.1176/appi.ajp.2017.16091059. View

11.

Allen C, Kluger B, Buard I . Safety of Transcranial Magnetic Stimulation in Children: A Systematic Review of the Literature. Pediatr Neurol. 2017; 68:3-17. PMC: 5346461. DOI: 10.1016/j.pediatrneurol.2016.12.009. View

12.

Whiteford H, Degenhardt L, Rehm J, Baxter A, Ferrari A, Erskine H . Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013; 382(9904):1575-86. DOI: 10.1016/S0140-6736(13)61611-6. View

13.

Dyke K, Pepes S, Chen C, Kim S, Sigurdsson H, Draper A . Comparing GABA-dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-high-field MRI. Neuroimage. 2017; 152:360-370. PMC: 5440178. DOI: 10.1016/j.neuroimage.2017.03.011. View

14.

Gabbay V, Mao X, Klein R, Ely B, Babb J, Panzer A . Anterior cingulate cortex γ-aminobutyric acid in depressed adolescents: relationship to anhedonia. Arch Gen Psychiatry. 2011; 69(2):139-49. PMC: 3711232. DOI: 10.1001/archgenpsychiatry.2011.131. View

15.

OReardon J, Solvason H, Janicak P, Sampson S, Isenberg K, Nahas Z . Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry. 2007; 62(11):1208-16. DOI: 10.1016/j.biopsych.2007.01.018. View

16.

Cullen K, Jasberg S, Nelson B, Klimes-Dougan B, Lim K, Croarkin P . Seizure Induced by Deep Transcranial Magnetic Stimulation in an Adolescent with Depression. J Child Adolesc Psychopharmacol. 2016; 26(7):637-41. PMC: 5118961. DOI: 10.1089/cap.2016.0070. View

17.

Ziemann U . Pharmacology of TMS. Suppl Clin Neurophysiol. 2003; 56:226-31. View

18.

Hu S, Wang S, Zhang M, Wang J, Hu J, Huang M . Repetitive transcranial magnetic stimulation-induced seizure of a patient with adolescent-onset depression: a case report and literature review. J Int Med Res. 2011; 39(5):2039-44. DOI: 10.1177/147323001103900552. View

19.

Donaldson A, Gordon M, Melvin G, Barton D, Fitzgerald P . Addressing the needs of adolescents with treatment resistant depressive disorders: a systematic review of rTMS. Brain Stimul. 2014; 7(1):7-12. DOI: 10.1016/j.brs.2013.09.012. View

20.

Wall C, Croarkin P, Maroney-Smith M, Haugen L, Baruth J, Frye M . Magnetic Resonance Imaging-Guided, Open-Label, High-Frequency Repetitive Transcranial Magnetic Stimulation for Adolescents with Major Depressive Disorder. J Child Adolesc Psychopharmacol. 2016; 26(7):582-9. PMC: 5035831. DOI: 10.1089/cap.2015.0217. View