» Articles » PMID: 30373008

Profiling the Impact of Thermal Processing on Black Raspberry Phytochemicals Using Untargeted Metabolomics

Overview
Journal Food Chem
Date 2018 Oct 31
PMID 30373008
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Clinical and laboratory studies have implicated black raspberries (BRBs) and their associated phytochemicals in the modulation of several chronic diseases. Most research on the health benefits of BRBs is conducted using freeze-dried or otherwise minimally processed products, yet BRBs are typically consumed as thermally processed goods like jams and syrups. The objective of this work was to profile the chemical changes that result from thermal processing of BRB powder into a nectar beverage. Using an untargeted UHPLC-QTOF-MS metabolomics approach, key degradation products of anthocyanins were identified along with several other proposed phenolic degradants. The effects of processing on other key BRB compound groups, including ellagitannins, are also discussed. This work demonstrates the utility of an untargeted metabolomics approach in describing the chemistry of complex food systems and provides a foundation for future research on the impact of processing on BRB product bioactivity.

Citing Articles

Berries vs. Disease: Revenge of the Phytochemicals.

Lamenza F, Upadhaya P, Roth P, Shrestha S, Jagadeesha S, Horn N Pharmaceuticals (Basel). 2024; 17(1).

PMID: 38256917 PMC: 10818490. DOI: 10.3390/ph17010084.


Berry Extracts and Their Bioactive Compounds Mitigate LPS and DNFB-Mediated Dendritic Cell Activation and Induction of Antigen Specific T-Cell Effector Responses.

Upadhaya P, Lamenza F, Shrestha S, Roth P, Jagadeesha S, Pracha H Antioxidants (Basel). 2023; 12(9).

PMID: 37759970 PMC: 10525528. DOI: 10.3390/antiox12091667.


Effects of Drying Treatments on Nutritional Compositions, Volatile Flavor Compounds, and Bioactive Substances of Broad Beans.

Li S, Liu F, Wu M, Li Y, Song X, Yin J Foods. 2023; 12(11).

PMID: 37297405 PMC: 10252730. DOI: 10.3390/foods12112160.


Untargeted Metabolomics Reveals New Markers of Food Processing for Strawberry and Apple Purees.

Salazar-Orbea G, Garcia-Villalba R, Sanchez-Siles L, Tomas-Barberan F, Garcia C Molecules. 2022; 27(21).

PMID: 36364102 PMC: 9653871. DOI: 10.3390/molecules27217275.


Vacuum pressure combined with osmosonication as an innovative pre-drying technique for Ghanaian ginger: Evidence from the metabolome and quality characteristics of the dried product.

Alolga R, Osae R, Apaliya M, Ibrahim T, Ahmed M, Kwaw E Ultrason Sonochem. 2021; 80:105841.

PMID: 34826726 PMC: 8633365. DOI: 10.1016/j.ultsonch.2021.105841.


References
1.
Gu L, Kelm M, Hammerstone J, Beecher G, Holden J, Haytowitz D . Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation. J Agric Food Chem. 2003; 51(25):7513-21. DOI: 10.1021/jf034815d. View

2.
Heleno S, Martins A, Queiroz M, Ferreira I . Bioactivity of phenolic acids: metabolites versus parent compounds: a review. Food Chem. 2014; 173:501-13. DOI: 10.1016/j.foodchem.2014.10.057. View

3.
Hou D, Kai K, Li J, Lin S, Terahara N, Wakamatsu M . Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms. Carcinogenesis. 2003; 25(1):29-36. DOI: 10.1093/carcin/bgg184. View

4.
Howard L, Prior R, Liyanage R, Lay J . Processing and storage effect on berry polyphenols: challenges and implications for bioactive properties. J Agric Food Chem. 2012; 60(27):6678-93. DOI: 10.1021/jf2046575. View

5.
Teegarden M, Knobloch T, Weghorst C, Cooperstone J, Peterson D . Storage conditions modulate the metabolomic profile of a black raspberry nectar with minimal impact on bioactivity. Food Funct. 2018; 9(9):4593-4601. PMC: 6146023. DOI: 10.1039/c8fo00639c. View