Vitamin D Deficiency and Supplementation in Critical Illness-the Known Knowns and Known Unknowns

Overview

Journal Crit Care

Specialty Critical Care

Date 2018 Oct 30

PMID 30371341

Citations 23

Authors

Priya Nair

Balasubramaniam Venkatesh

Jacqueline R Center

Affiliations

Soon will be listed here.

Abstract

The burgeoning literature on vitamin D deficiency and supplementation over the past decade or so has generated a greater understanding of some areas but also an appreciation of the many areas of equipoise. This is particularly relevant in the field of critical care with the heterogeneous patient populations, the severity and duration of illness and the frequency of comorbid conditions.This review aims to summarise the current knowledge base of vitamin D deficiency within the context of critical illness-"the known knowns"-and also highlight the areas of recognised uncertainty-"the known unknowns". It acknowledges the fact that there may well be other knowledge gaps of clinical relevance of which we are currently unaware-"the unknown unknowns".

Citing Articles

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The Immunomodulatory Activity of High Doses of Vitamin D in Critical Care Patients with Severe SARS-CoV-2 Pneumonia-A Randomized Controlled Trial.

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25-hydroxyvitamin D and parathyroid hormone in new onset sepsis: A prospective study in critically ill patients.

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A Comprehensive Review of the Immunomodulatory Effects of Vitamin D in Sepsis.

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Positive Association of Urinary Dimethylarsinic Acid (DMA) with Serum 25(OH)D in Adults Living in an Area of Water-Borne Arsenicosis in Shanxi, China.

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