The JPOST Environment: an Integrated Proteomics Data Repository and Database

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2018 Oct 9

PMID 30295851

Citations 44

Authors

Yuki Moriya

Shin Kawano

Shujiro Okuda

Yu Watanabe

Masaki Matsumoto

Tomoyo Takami

Daiki Kobayashi

Yoshinori Yamanouchi

Norie Araki

Akiyasu C Yoshizawa

Tsuyoshi Tabata

Mio Iwasaki

Naoyuki Sugiyama

Satoshi Tanaka

Susumu Goto

Yasushi Ishihama

Affiliations

Soon will be listed here.

Abstract

Rapid progress is being made in mass spectrometry (MS)-based proteomics, yielding an increasing number of larger datasets with higher quality and higher throughput. To integrate proteomics datasets generated from various projects and institutions, we launched a project named jPOST (Japan ProteOme STandard Repository/Database, https://jpostdb.org/) in 2015. Its proteomics data repository, jPOSTrepo, began operations in 2016 and has accepted more than 10 TB of MS-based proteomics datasets in the past two years. In addition, we have developed a new proteomics database named jPOSTdb in which the published raw datasets in jPOSTrepo are reanalyzed using standardized protocol. jPOSTdb provides viewers showing the frequency of detected post-translational modifications, the co-occurrence of phosphorylation sites on a peptide and peptide sharing among proteoforms. jPOSTdb also provides basic statistical analysis tools to compare proteomics datasets.

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