Patch Testing Pearls

Overview

Journal Clin Rev Allergy Immunol

Specialty Allergy & Immunology

Date 2018 Oct 1

PMID 30269296

Citations 5

Authors

Betty A Uyesugi

Michael P Sheehan

Affiliations

Soon will be listed here.

Abstract

Dermatitis is one of the most common illnesses encountered by healthcare providers and the causes are numerous. Contact dermatitis is the form of dermatitis resulting from contact with the environment, and it may be either irritant or allergic in nature. Patch testing has been the gold standard for diagnosis of allergic contact dermatitis since its formal description over 100 years ago by Jadassohn. While this diagnostic tool may seem simple to us today, there are numerous potential points for error that the practitioner must keep in mind. Patient selection, technique of patch test placement, allergen selection, patch test reading and interpretation, and patient management all must be considered. To simply apply a given set of test allergens indiscriminately and not be prepared to interpret the results accurately with patient education and management in mind would be a great failure. Conversely, with experience and the proper knowledge base some of the most complex dermatitis questions can be answered.

Citing Articles

A Comprehensive Analysis of Immunoglobulin E Levels, Allergen-Specific Sensitivities, and Clinical Manifestations in Allergic Dermatological Conditions: A Multicenter Retrospective Study in China.

Zhao J, Liang S, Zhou B, Li M, Li L Clin Cosmet Investig Dermatol. 2024; 17:499-512.

PMID: 38444403 PMC: 10913895. DOI: 10.2147/CCID.S451117.

Artificial Intelligence That Predicts Sensitizing Potential of Cosmetic Ingredients with Accuracy Comparable to Animal and In Vitro Tests-How Does the Infotechnomics Compare to Other "Omics" in the Cosmetics Safety Assessment?.

Kalicinska J, Wisniowska B, Polak S, Spiewak R Int J Mol Sci. 2023; 24(7).

PMID: 37047774 PMC: 10094956. DOI: 10.3390/ijms24076801.

Contact Dermatitis: Classifications and Management.

Li Y, Li L Clin Rev Allergy Immunol. 2021; 61(3):245-281.

PMID: 34264448 DOI: 10.1007/s12016-021-08875-0.

A dog lover's dilemma: Airborne allergic contact dermatitis to tylosin.

Kale A, Gaspari A JAAD Case Rep. 2020; 7:100-102.

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Medical devices in allergy practice.

Popov T, Passalacqua G, Gonzalez-Diaz S, Plavec D, Braido F, Garcia-Abujeta J World Allergy Organ J. 2020; 13(10):100466.

PMID: 33024482 PMC: 7529824. DOI: 10.1016/j.waojou.2020.100466.

References

Egan C, Rallis T, Meadows K, Krueger G . Low-dose oral methotrexate treatment for recalcitrant palmoplantar pompholyx. J Am Acad Dermatol. 1999; 40(4):612-4. DOI: 10.1016/s0190-9622(99)70446-9. View

Katsarma G, Gawkrodger D . Suspected fragrance allergy requires extended patch testing to individual fragrance allergens. Contact Dermatitis. 1999; 41(4):193-7. DOI: 10.1111/j.1600-0536.1999.tb06129.x. View

Bruze M, Conde-Salazar L, Goossens A, Kanerva L, White I . Thoughts on sensitizers in a standard patch test series. The European Society of Contact Dermatitis. Contact Dermatitis. 1999; 41(5):241-50. DOI: 10.1111/j.1600-0536.1999.tb06154.x. View

Isaksson M, Andersen K, Brandao F, Bruynzeel D, Bruze M, Camarasa J . Patch testing with corticosteroid mixes in Europe. A multicentre study of the EECDRG. Contact Dermatitis. 2000; 42(1):27-35. DOI: 10.1034/j.1600-0536.2000.042001027.x. View

Jonker M, Bruynzeel D . The outcome of an additional patch-test reading on days 6 or 7. Contact Dermatitis. 2000; 42(6):330-5. DOI: 10.1034/j.1600-0536.2000.042006330.x. View

Ashida Y, Denda M, Hirao T . Histamine H1 and H2 receptor antagonists accelerate skin barrier repair and prevent epidermal hyperplasia induced by barrier disruption in a dry environment. J Invest Dermatol. 2001; 116(2):261-5. DOI: 10.1046/j.1523-1747.2001.01238.x. View

Hutchings C, Shum K, Gawkrodger D . Occupational contact dermatitis has an appreciable impact on quality of life. Contact Dermatitis. 2001; 45(1):17-20. DOI: 10.1034/j.1600-0536.2001.045001017.x. View

Suneja T, Belsito D . Comparative study of Finn Chambers and T.R.U.E. test methodologies in detecting the relevant allergens inducing contact dermatitis. J Am Acad Dermatol. 2001; 45(6):836-9. DOI: 10.1067/mjd.2001.117396. View

Anderson R, Rajagopalan R . Effects of allergic dermatosis on health-related quality of life. Curr Allergy Asthma Rep. 2002; 1(4):309-15. DOI: 10.1007/s11882-001-0041-3. View

10.

Meding B, Jarvholm B . Hand eczema in Swedish adults - changes in prevalence between 1983 and 1996. J Invest Dermatol. 2002; 118(4):719-23. DOI: 10.1046/j.1523-1747.2002.01718.x. View

11.

THOMSON K, Wilkinson S, Sommer S, Pollock B . Eczema: quality of life by body site and the effect of patch testing. Br J Dermatol. 2002; 146(4):627-30. DOI: 10.1046/j.1365-2133.2002.04692.x. View

12.

Duarte I, Lazzarini R, Buense R . Interference of the position of substances in an epicutaneous patch test battery with the occurrence of false-positive results. Am J Contact Dermat. 2002; 13(3):125-32. View

13.

Mitchell J . The angry back syndrome: eczema creates eczema. Contact Dermatitis. 1975; 1(4):193-4. DOI: 10.1111/j.1600-0536.1975.tb05380.x. View

14.

Coenraads P, Bleumink E, Nater J . Susceptibility to primary irritants: age dependence and relation to contact allergic reactions. Contact Dermatitis. 1975; 1(6):377-81. DOI: 10.1111/j.1600-0536.1975.tb05478.x. View

15.

Diepgen T . Occupational skin-disease data in Europe. Int Arch Occup Environ Health. 2003; 76(5):331-8. DOI: 10.1007/s00420-002-0418-1. View

16.

Saripalli Y, Achen F, Belsito D . The detection of clinically relevant contact allergens using a standard screening tray of twenty-three allergens. J Am Acad Dermatol. 2003; 49(1):65-9. DOI: 10.1067/mjd.2003.489. View

17.

Nettis E, Marcandrea M, Colanardi M, Paradiso M, Ferrannini A, Tursi A . Results of standard series patch testing in patients with occupational allergic contact dermatitis. Allergy. 2003; 58(12):1304-7. DOI: 10.1046/j.1398-9995.2003.00346.x. View

18.

Kadyk D, McCarter K, Achen F, Belsito D . Quality of life in patients with allergic contact dermatitis. J Am Acad Dermatol. 2003; 49(6):1037-48. DOI: 10.1016/s0190-9622(03)02112-1. View

19.

Griffiths C, Dubertret L, Ellis C, Finlay A, Finzi A, Ho V . Ciclosporin in psoriasis clinical practice: an international consensus statement. Br J Dermatol. 2004; 150 Suppl 67:11-23. DOI: 10.1111/j.0366-077X.2004.05949.x. View

20.

Belsito D . Patch testing with a standard allergen ("screening") tray: rewards and risks. Dermatol Ther. 2004; 17(3):231-9. DOI: 10.1111/j.1396-0296.2004.04033.x. View