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Simultaneous Bilateral Tubal Ectopic Pregnancy After Intracytoplasmic Sperm Injection and Embryo Transfer, in a Patient with Stage 3 Endometriosis

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Date 2018 Sep 27
PMID 30254915
Citations 3
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Abstract

Introduction: The incidence of extrauterine pregnancy increases to 2-12% following fertilization -embryo transfer. Several pathogenic theories have been suggested, including abnormal hormonal secretion or exogenous hormones administered in assisted reproductive technology (ART).

Case Report: A 32-year-oId nulliparous woman with primary infertility and Stage 3 endometriosis was treated by ART with intracytoplasmic sperm injection and embryo transfer. The patient showed simultaneous bilateral extrauterine pregnancy, managed by laparoscopic salpingectomy.

Discussion: The various possible pathophysiological mechanisms are described, with a review of the literature on simultaneous bilateral extrauterine pregnancy following ART. In pregnancies following ART, ectopic pregnancy should always be screened for by serum β-human chorionic gonadotropin monitoring and transvaginal ultrasound until the implantation site can be confirmed as the incidence is higher than in spontaneous pregnancy. Even if serum β-human chorionic gonadotropin concentration increases normally, possible bilateral ectopic pregnancy should always be investigated if no intrauterine gestational sac can be seen.

Citing Articles

A Rare Case of Bilateral Tubal Ectopic Pregnancy Following Intracytoplasmic Sperm Injection-Embryo Transfer (ICSI-ET).

Acet F, Goker E, Hortu I, Sahin G, Tavmergen E Rev Bras Ginecol Obstet. 2020; 42(3):165-168.

PMID: 32232825 PMC: 10316848. DOI: 10.1055/s-0040-1708093.


Previously asymptomatic ruptured tubal ectopic pregnancy at over 10 weeks' gestation: Two case reports.

Gauvin C, Amberger M, Louie K, Argeros O Case Rep Womens Health. 2018; 21:e00089.

PMID: 30591911 PMC: 6305792. DOI: 10.1016/j.crwh.2018.e00089.


Bilateral Tubal Pregnancy without Known Risk Factor.

Zamane H, Yameogo B, Kain P, Kabore F, Sawadogo Y, Kiemtore S Case Rep Obstet Gynecol. 2017; 2017:4356036.

PMID: 29181210 PMC: 5664235. DOI: 10.1155/2017/4356036.

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