Risk Factors for Ectopic Pregnancy in 556 Pregnancies After in Vitro Fertilization: Implications for Preventive Management

Overview

Journal Fertil Steril

Specialty Reproductive Medicine

Date 1991 Oct 1

PMID 1915943

Citations 18

Authors

J B Dubuisson

F X Aubriot

L Mathieu

H Foulot

L Mandelbrot

J B de Joliere

Affiliations

Soon will be listed here.

Abstract

Objective: To analyze risk factors for ectopic pregnancy (EP) after in vitro fertilization (IVF).

Design: A retrospective study of IVF pregnancies was performed between November 1983 and December 1989.

Setting: This study was conducted in a tertiary care center, the Port-Royal University Hospital.

Patients: Patients' records were reviewed for 48 EP and 508 intrauterine pregnancies obtained by IVF.

Interventions: Forty-six salpingectomies were performed for EP after IVF.

Main Outcome Measure: We evaluated the impact on the ectopic rate of tubal status, the type of ovarian stimulation and luteal phase support, and the number of embryos transferred.

Results: Forty-three of 48 EP occurred in patients with tubal infertility. The rate of EP was significantly higher when the indication was tubal (11.1%) than when it was endometriosis (2.1%) or unexplained infertility (3.4%). Pathological findings revealed tubal lesions in all 46 salpingectomies.

Conclusions: Ectopic pregnancy after IVF appears related to pre-existing tubal pathology. However, routine prophylactic salpingectomy to prevent the risk of EP does not appear justified.

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Katler Q, Pflugner L, Martinez A Case Rep Obstet Gynecol. 2018; 2018:7539713.

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