Prevalence of Chlamydia Trachomatis and Neisseria Gonorrhoeae Infections Among Pregnant Women and Eye Colonization of Their Neonates at Birth Time, Shiraz, Southern Iran

Overview

Journal BMC Infect Dis

Publisher Biomed Central

Specialty Infectious Diseases

Date 2018 Sep 26

PMID 30249196

Citations 5

Authors

Bahman Pourabbas

Zahra Rezaei

Jalal Mardaneh

Mozhgan Shahian

Abdolvahab Alborzi

Affiliations

Soon will be listed here.

Abstract

Background: Chlamydia trachomatis and Neisseria gonorrhoeae are the two common transmissible pathogens from pregnant women to their neonates. Given the lack of routine screening and treatment of pregnant women in some areas, the possibility of transmission rises. This study seeks to determine the prevalence of C. trachomatis and N. gonorrhoeae in the pregnant women with no clinical symptoms and the vertical transmission rate to their neonates.

Methods: The study was conducted on endocervical and eye swab samples of 239 pregnant women and their neonates. Identification was based on PCR method.

Results: The prevalence rates of C.trachomatis in women and neonates were 37/239 (15.5%) and 28/239 (11.7%), and for N. gonorrhoeae 3/239 (1.3%), 1/239 (0.4%), respectively. The vertical transmission rates to the neonates were 28/37(75.6%) for C. trachomatis and 1/3 for N. gonorrhoeae.

Conclusions: In the areas with a high prevalence of chlamydial or gonococcal infections, and in the absence of screening and treatment of the pregnant women, ocular prophylaxis with antibiotics is suggested as a part of routine neonatal care program for the prevention of chlamydial and gonococcal ophthalmia.

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