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Multifocal Thymic Cysts with Cholesterol Granuloma

Overview
Journal Respirol Case Rep
Date 2018 Sep 7
PMID 30186607
Citations 6
Authors
Shunichi Nagata
Misa Ishihara
Mitsugu Omasa
Takao Nakanishi
Hideki Motoyama
Affiliations
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Abstract

A 56-year-old female presented to our department with chest discomfort. Contrast-enhanced computed tomography (CT) revealed a cyst and nodule in the anterior mediastinum; positron emission tomography-CT showed an increased uptake in the nodule. Total thymectomy was performed to obtain a definitive diagnosis and treatment. A pathological diagnosis of multifocal thymic cysts with cholesterol granuloma was made. Microscopic examination revealed different-sized cysts scattered in the thymus. These cysts were filled with cholesterol clefts and manifested three different phase characters. The nodule comprised granuloma-containing cholesterol clefts. We report a rare case of a patient whose histopathology presented a series of cholesterol granuloma formations.

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