Extract Improves a High-sucrose Diet-induced Metabolic Disorder in

Overview

Journal Exp Ther Med

Specialty Pathology

Date 2018 Sep 7

PMID 30186490

Citations 12

Authors

Ye Bai

Kun Li

Jiayao Shao

Qiuxiang Luo

Li Hua Jin

Affiliations

Soon will be listed here.

Abstract

(CI) is a traditional medicinal plant used in the treatment of inflammatory diseases. However, the pharmacological role of CI in metabolic diseases, especially in diseases induced by insulin metabolism disorders, remains poorly understood. In the present study, () were fed with high-sugar diet (HSD) to induce a model similar to Type 2 diabetes (T2D) in order to determine whether CI extracts improve the metabolic disorder. It was demonstrated that the CI extracts could improve growth rate, body size, lifespan, reproductive capacity and fat storage, and CI especially improved the fat metabolism and cell size in and mutant flies. In conclusion, the present study provides novel evidence that CI may be an effective drug for the treatment of T2D.

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