Frequency of Human Parvovirus B19 Among Patients with Respiratory Infection in Iran

Overview

Journal Med J Islam Repub Iran

Specialty General Medicine

Date 2018 Aug 31

PMID 30159289

Citations 6

Authors

Ahmad Tavakoli

Seyed Hamidreza Monavari

Hamidreza Mollaei

Farah Bokharaei-Salim

Maryam Esghaei

Hossein Keyvani

Hadi Ghaffari

Affiliations

Soon will be listed here.

Abstract

Human parvovirus B19 was known as one of the possible cause of mild respiratory tract diseases in previous studies. However, there are some reports of acute obstructive respiratory disease and severe pneumonia. The purpose of current study was to assess the prevalence and clinical features of parvovirus B19 in respiratory infection. This study was conducted on 156 patients diagnosed with respiratory infection at the Iran University of Medical Sciencesaffiliated hospitals. After extraction of viral DNA from swab samples, detection of parvovirus B19 was performed by real-time PCR assay. In 156 patient's samples, parvovirus B19 was found in 8 (5.1 %) cases including 5 males (5.9%) and 3 females (4.1%). The most common clinical symptoms were wheezing (100%), tachypnea (100%), fever (75%) and rhinorrhea/pharyngitis (75%). This is the first attempt to assess the prevalence of parvovirus B19 infection in Iranian patients with respiratory infection. The low frequency of parvovirus B19 detected in our study does not support the role of this virus in the development of respiratory infection. However, further studies are needed to better evaluate the etiological role of parvovirus B19 in respiratory infection.

Citing Articles

Molecular and serological markers of human parvovirus B19 infection in blood donors: A systematic review and meta-analysis.

Farahmand M, Tavakoli A, Ghorbani S, Monavari S, Kiani S, Minaeian S Asian J Transfus Sci. 2021; 15(2):212-222.

PMID: 34908757 PMC: 8628227. DOI: 10.4103/ajts.ajts_185_20.

Human Parvoviruses May Affect the Development and Clinical Course of Meningitis and Meningoencephalitis.

Vilmane A, Terentjeva A, Tamosiunas P, Suna N, Suna I, Petraityte-Burneikiene R Brain Sci. 2020; 10(6).

PMID: 32503112 PMC: 7349785. DOI: 10.3390/brainsci10060339.

Association between Parvovirus B19 and anemia in HIV-infected patients.

Nouri M, Kamakifar P, Khodabandehlou N, Nahand J, Tavakoli A, Norooznezhad F Med J Islam Repub Iran. 2020; 33:137.

PMID: 32280643 PMC: 7137816. DOI: 10.34171/mjiri.33.137.

The molecular epidemiology of respiratory viruses in military trainees in Iran.

Tavakoli A, Karbalaie Niya M, Bokharaei-Salim F, Farahmand M, Izadi M, Dorostkar R Med J Islam Repub Iran. 2019; 33:40.

PMID: 31456964 PMC: 6708098. DOI: 10.34171/mjiri.33.40.

Evolutionary aspects of Parvovirus B-19V associated diseases and their pathogenesis patterns with an emphasis on vaccine development.

Das P, Chatterjee K, Roy Chattopadhyay N, Choudhuri T Virusdisease. 2019; 30(1):32-42.

PMID: 31143830 PMC: 6517593. DOI: 10.1007/s13337-019-00525-6.

References

Nagaharu K, Sugimoto Y, Hoshi Y, Yamaguchi T, Ito R, Matsubayashi K . Persistent symptomatic parvovirus B19 infection with severe thrombocytopenia transmitted by red blood cell transfusion containing low parvovirus B19 DNA levels. Transfusion. 2017; 57(6):1414-1418. DOI: 10.1111/trf.14088. View

Marano G, Vaglio S, Pupella S, Facco G, Calizzani G, Candura F . Human Parvovirus B19 and blood product safety: a tale of twenty years of improvements. Blood Transfus. 2015; 13(2):184-96. PMC: 4385066. DOI: 10.2450/2014.0174.14. View

Zaki S . Detection of human parvovirus B19 in cancer patients using ELISA and real-time PCR. Indian J Med Microbiol. 2012; 30(4):407-10. DOI: 10.4103/0255-0857.103760. View

Frotscher B, Salignac S, Morlon L, Bonmati C, Jeulin H, Venard V . [Neutropenia and/or thrombocytopenia due to acute parvovirus B19 infection]. Ann Biol Clin (Paris). 2009; 67(3):343-8. DOI: 10.1684/abc.2009.0324. View

Romero-Espinoza J, Moreno-Valencia Y, Coronel-Tellez R, Castillejos-Lopez M, Hernandez A, Dominguez A . Virome and bacteriome characterization of children with pneumonia and asthma in Mexico City during winter seasons 2014 and 2015. PLoS One. 2018; 13(2):e0192878. PMC: 5813968. DOI: 10.1371/journal.pone.0192878. View

Monavari S, Noorbakhsh S, Mollaie H, Fazlalipour M, Kiasari B . Human Bocavirus in Iranian children with acute gastroenteritis. Med J Islam Repub Iran. 2014; 27(3):127-31. PMC: 3917485. View

Lysholm F, Wetterbom A, Lindau C, Darban H, Bjerkner A, Fahlander K . Characterization of the viral microbiome in patients with severe lower respiratory tract infections, using metagenomic sequencing. PLoS One. 2012; 7(2):e30875. PMC: 3280267. DOI: 10.1371/journal.pone.0030875. View

Lamont R, Sobel J, Vaisbuch E, Kusanovic J, Mazaki-Tovi S, Kim S . Parvovirus B19 infection in human pregnancy. BJOG. 2010; 118(2):175-86. PMC: 3059196. DOI: 10.1111/j.1471-0528.2010.02749.x. View

Javanmard D, Ziaee M, Ghaffari H, Namaei M, Tavakoli A, Mollaei H . Human parvovirus B19 and parvovirus 4 among Iranian patients with hemophilia. Blood Res. 2018; 52(4):311-315. PMC: 5762743. DOI: 10.5045/br.2017.52.4.311. View

10.

Kazama I, Sasagawa N, Nakajima T . Complete remission of human parvovirus b19 associated symptoms by loxoprofen in patients with atopic predispositions. Case Rep Med. 2012; 2012:703281. PMC: 3348632. DOI: 10.1155/2012/703281. View

11.

van Asseldonk D, Kanis B, de Boer N, van Bodegraven A . Leukopenia due to parvovirus B19 in a Crohn's disease patient using azathioprine. Digestion. 2009; 79(4):211-4. DOI: 10.1159/000212778. View

12.

Rogo L, Mokhtari-Azad T, Kabir M, Rezaei F . Human parvovirus B19: a review. Acta Virol. 2014; 58(3):199-213. DOI: 10.4149/av_2014_03_199. View

13.

Yaguchi D, Marui N, Matsuo M . Three Adult Cases of HPV-B19 Infection with Concomitant Leukopenia and Low Platelet Counts. Clin Med Insights Case Rep. 2015; 8:19-22. PMC: 4345940. DOI: 10.4137/CCRep.S18085. View

14.

Shih H, Wang H, Su I, Hsu H, Wang J, Sun H . Viral Respiratory Tract Infections in Adult Patients Attending Outpatient and Emergency Departments, Taiwan, 2012-2013: A PCR/Electrospray Ionization Mass Spectrometry Study. Medicine (Baltimore). 2015; 94(38):e1545. PMC: 4635751. DOI: 10.1097/MD.0000000000001545. View

15.

Arabzadeh S, Alizadeh F, Tavakoli A, Mollaei H, Bokharaei-Salim F, Karimi G . Human parvovirus B19 in patients with beta thalassemia major from Tehran, Iran. Blood Res. 2017; 52(1):50-54. PMC: 5383588. DOI: 10.5045/br.2017.52.1.50. View

16.

Shabani Z, Esghaei M, Keyvani H, Shabani F, Sarmadi F, Mollaie H . Relation between parvovirus B19 infection and fetal mortality and spontaneous abortion. Med J Islam Repub Iran. 2015; 29:197. PMC: 4476220. View

17.

Giorgio E, De Oronzo M, Iozza I, Di Natale A, Cianci S, Garofalo G . Parvovirus B19 during pregnancy: a review. J Prenat Med. 2012; 4(4):63-6. PMC: 3279187. View

18.

Costa C, Terlizzi M, Solidoro P, Libertucci D, Bergallo M, Cavallo R . Detection of parvovirus B19 in the lower respiratory tract. J Clin Virol. 2009; 46(2):150-3. PMC: 7172881. DOI: 10.1016/j.jcv.2009.06.026. View