Role of Ner Protein in Bacteriophage Mu Transposition

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1986 Aug 1

PMID 3015876

Citations 16

Authors

N Goosen

P Van de Putte

Affiliations

Soon will be listed here.

Abstract

The Ner protein of bacteriophage Mu negatively regulates transcription initiated at the early promoter and at the major repressor promoter. The construction and isolation of a Ner- mutant of Mu is described. Ner is an essential function for Mu, because the mutant phage only forms plaques when complemented for Ner. Mutations in the repressor protein did not abolish the need for Ner. However, when transcription of the repressor gene c was blocked by deleting the major repressor promoter, Ner was no longer essential for normal Mu development.

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Controlling DNA degradation from a distance: a new role for the Mu transposition enhancer.

Choi W, Saha R, Jang S, Harshey R Mol Microbiol. 2014; 94(3):595-608.

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Identification of an unknown promoter, OUTIIp, within the IS10R element.

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Insertion sequences.

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The integration host factor-DNA complex upstream of the early promoter of bacteriophage Mu is functionally symmetric.

van Ulsen P, Hillebrand M, Zulianello L, Van de Putte P, Goosen N J Bacteriol. 1997; 179(9):3073-5.

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