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Serum Uric Acid Levels and Hyperuricemia in Patients with Psoriasis: a Hospital-based Cross-sectional Study

Overview
Journal An Bras Dermatol
Specialty Dermatology
Date 2018 Aug 30
PMID 30156637
Citations 6
Authors
Xin-Yu Gui
Hong-Zhong Jin
Zhen-Jie Wang
Teng-da Xu
Affiliations
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Abstract

A hospital-based cross-sectional study was performed, including 117 psoriatic patients and 117 controls matched for age, gender, and body mass index. Psoriatic patients had higher levels of serum uric acid (6.25 ± 1.62 vs 5.71 ± 1.35 mg/dl; P=0.019) and significantly greater prevalence of hyperuricemia (31.6% vs 16.2%; P=0.009) than individuals without psoriasis. Psoriatic patients had significantly higher serum uric acid than controls in subjects without metabolic syndrome. Multivariate logistic regression analysis showed that psoriasis can be a strong predictor of hyperuricemia (odds ratio 2.61; 95% confidence interval 1.34-5.00; P=0.004).

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