Sinus Membrane Elevation with Heterologous Cortical Lamina: A Randomized Study of a New Surgical Technique for Maxillary Sinus Floor Augmentation Without Bone Graft

Overview

Journal Materials (Basel)

Publisher MDPI

Date 2018 Aug 22

PMID 30126102

Citations 21

Authors

Antonio Scarano

Pablo Santos de Oliveira

Tonino Traini

Felice Lorusso

Affiliations

Soon will be listed here.

Abstract

Background: The aim of this randomized controlled clinical trial was to compare the efficacy of two different techniques for maxillary sinus augmentation using a lateral window approach: Heterologous cortical lamina without any grafting material versus 100% collagenated granular collagen porcine bone.

Methods: Twenty-three healthy patients with not relevant past medical history (14 women and 9 men, non-smokers, mean age 52 years, range 48⁻65 years) were included. In Group I, the sinus was filled with collagen porcine bone (Geno-os, OsteoBiol, Turin, Italy) and a collagen membrane (Evolution, OsteoBiol, Turin, Italy) was used to close the lateral window of the sinus. In Group II, the sinus was treated with heterologous cortical lamina only (Lamina, OsteoBiol, Turin, Italy).

Results: There was a statistically significant difference in the surgical time required to complete the augmentation procedures: 18.3 ± 2.1 min for lamina treated sites versus 12.5 ± 3.1 min for porcine bone treated sites. In Group I, the mean volume of the graft was 3101 ± 321 mm³ in the immediate postoperative examination (5⁻7 days), while after a six-month healing period it was 2716.7 ± 432 mm³.

Conclusion: This study demonstrates that the use of heterologous cortical lamina is a valid technique for the mechanical support of sinus membranes resulting in only bone tissue formation and not mixed with the graft. The graft material was biocompatible and not completely resorbed after six months, although the remains were integrated into the bone.

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References

Hatano N, Shimizu Y, Ooya K . A clinical long-term radiographic evaluation of graft height changes after maxillary sinus floor augmentation with a 2:1 autogenous bone/xenograft mixture and simultaneous placement of dental implants. Clin Oral Implants Res. 2004; 15(3):339-45. DOI: 10.1111/j.1600-0501.2004.00996.x. View

Scarano A, Perrotti V, Carinci F, Shibli J . Removal of a migrated dental implant from the maxillary sinus after 7 years: a case report. Oral Maxillofac Surg. 2010; 15(4):239-43. DOI: 10.1007/s10006-010-0243-8. View

Wallace S, Froum S . Effect of maxillary sinus augmentation on the survival of endosseous dental implants. A systematic review. Ann Periodontol. 2004; 8(1):328-43. DOI: 10.1902/annals.2003.8.1.328. View

Scarano A, Piattelli A, Iezzi G, Varvara G . Spontaneous bone formation on the maxillary sinus floor in association with surgery to remove a migrated dental implant: a case report. Minerva Stomatol. 2014; 63(10):351-9. View

Scarano A, Ceccarelli M, Marchetti M, Piattelli A, Mortellaro C . Soft Tissue Augmentation with Autologous Platelet Gel and β-TCP: A Histologic and Histometric Study in Mice. Biomed Res Int. 2016; 2016:2078104. PMC: 4960330. DOI: 10.1155/2016/2078104. View

Scala A, Lang N, Velez J, Favero R, Bengazi F, Botticelli D . Effects of a collagen membrane positioned between augmentation material and the sinus mucosa in the elevation of the maxillary sinus floor. An experimental study in sheep. Clin Oral Implants Res. 2016; 27(11):1454-1461. DOI: 10.1111/clr.12762. View

Froum S, Tarnow D, Wallace S, Rohrer M, Cho S . Sinus floor elevation using anorganic bovine bone matrix (OsteoGraf/N) with and without autogenous bone: a clinical, histologic, radiographic, and histomorphometric analysis--Part 2 of an ongoing prospective study. Int J Periodontics Restorative Dent. 1999; 18(6):528-43. View

Jung Y, Chung S, Nam W, Cho I, Cha I, Park H . Spontaneous bone formation on the maxillary sinus floor in association with an extraction socket. Int J Oral Maxillofac Surg. 2007; 36(7):656-7. DOI: 10.1016/j.ijom.2007.01.013. View

Scarano A, Lorusso F, Arcangelo M, DArcangelo C, Celletti R, de Oliveira P . Lateral Sinus Floor Elevation Performed with Trapezoidal and Modified Triangular Flap Designs: A Randomized Pilot Study of Post-Operative Pain Using Thermal Infrared Imaging. Int J Environ Res Public Health. 2018; 15(6). PMC: 6025054. DOI: 10.3390/ijerph15061277. View

10.

Bayliss P, Bellavance K, Whitehead G, Abrams J, Aegerter S, Robbins H . Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish. Nat Chem Biol. 2006; 2(5):265-73. PMC: 1534118. DOI: 10.1038/nchembio778. View

11.

Piattelli A, Scarano A, Quaranta M . High-precision, cost-effective cutting system for producing thin sections of oral tissues containing dental implants. Biomaterials. 1997; 18(7):577-9. DOI: 10.1016/s0142-9612(96)00177-9. View

12.

Trubiani O, Zalzal S, Paganelli R, Marchisio M, Giancola R, Pizzicannella J . Expression profile of the embryonic markers nanog, OCT-4, SSEA-1, SSEA-4, and frizzled-9 receptor in human periodontal ligament mesenchymal stem cells. J Cell Physiol. 2010; 225(1):123-31. DOI: 10.1002/jcp.22203. View

13.

Shibli J, Faveri M, Ferrari D, Melo L, Garcia R, dAvila S . Prevalence of maxillary sinus septa in 1024 subjects with edentulous upper jaws: a retrospective study. J Oral Implantol. 2007; 33(5):293-6. DOI: 10.1563/1548-1336(2007)33[293:POMSSI]2.0.CO;2. View

14.

Scarano A, Cholakis A, Piattelli A . Histologic Evaluation of Sinus Grafting Materials After Peri-implantitis-Induced Failure: A Case Series. Int J Oral Maxillofac Implants. 2017; 32(2):e69-e75. DOI: 10.11607/jomi.5303. View

15.

Iida T, Martins Neto E, Botticelli D, Apaza Alccayhuaman K, Lang N, Xavier S . Influence of a collagen membrane positioned subjacent the sinus mucosa following the elevation of the maxillary sinus. A histomorphometric study in rabbits. Clin Oral Implants Res. 2017; 28(12):1567-1576. DOI: 10.1111/clr.13027. View

16.

Nannmark U, Sennerby L . The bone tissue responses to prehydrated and collagenated cortico-cancellous porcine bone grafts: a study in rabbit maxillary defects. Clin Implant Dent Relat Res. 2008; 10(4):264-70. DOI: 10.1111/j.1708-8208.2007.00080.x. View

17.

Scarano A, Inchingolo F, Murmura G, Traini T, Piattelli A, Lorusso F . Three-Dimensional Architecture and Mechanical Properties of Bovine Bone Mixed with Autologous Platelet Liquid, Blood, or Physiological Water: An In Vitro Study. Int J Mol Sci. 2018; 19(4). PMC: 5979420. DOI: 10.3390/ijms19041230. View

18.

Srouji S, Kizhner T, Ben David D, Riminucci M, Bianco P, Livne E . The Schneiderian membrane contains osteoprogenitor cells: in vivo and in vitro study. Calcif Tissue Int. 2008; 84(2):138-45. DOI: 10.1007/s00223-008-9202-x. View

19.

Scala A, Botticelli D, Faeda R, Garcia Rangel Jr I, de Oliveira J, Lang N . Lack of influence of the Schneiderian membrane in forming new bone apical to implants simultaneously installed with sinus floor elevation: an experimental study in monkeys. Clin Oral Implants Res. 2011; 23(2):175-181. DOI: 10.1111/j.1600-0501.2011.02227.x. View

20.

Caneva M, Lang N, Garcia Rangel I, Ferreira S, Caneva M, De Santis E . Sinus mucosa elevation using Bio-Oss or Gingistat collagen sponge: an experimental study in rabbits. Clin Oral Implants Res. 2016; 28(7):e21-e30. DOI: 10.1111/clr.12850. View