Potential Point-of-Care Microfluidic Devices to Diagnose Iron Deficiency Anemia

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2018 Aug 15

PMID 30103424

Citations 6

Authors

Boon Kar Yap

Siti NurArifah M Soair

Noor Azrina Talik

Wai Feng Lim

Lai Mei I

Affiliations

Soon will be listed here.

Abstract

Over the past 20 years, rapid technological advancement in the field of microfluidics has produced a wide array of microfluidic point-of-care (POC) diagnostic devices for the healthcare industry. However, potential microfluidic applications in the field of nutrition, specifically to diagnose iron deficiency anemia (IDA) detection, remain scarce. Iron deficiency anemia is the most common form of anemia, which affects billions of people globally, especially the elderly, women, and children. This review comprehensively analyzes the current diagnosis technologies that address anemia-related IDA-POC microfluidic devices in the future. This review briefly highlights various microfluidics devices that have the potential to detect IDA and discusses some commercially available devices for blood plasma separation mechanisms. Reagent deposition and integration into microfluidic devices are also explored. Finally, we discuss the challenges of insights into potential portable microfluidic systems, especially for remote IDA detection.

Citing Articles

Advances in Microfluidics for Single Red Blood Cell Analysis.

Grigorev G, Lebedev A, Wang X, Qian X, Maksimov G, Lin L Biosensors (Basel). 2023; 13(1).

PMID: 36671952 PMC: 9856164. DOI: 10.3390/bios13010117.

Efficient and Simple Paper-Based Assay for Plasma Separation Using Universal Anti-H Agglutinating Antibody.

Al-Tamimi M, Altarawneh S, Alsallaq M, Ayoub M ACS Omega. 2022; 7(44):40109-40115.

PMID: 36385881 PMC: 9647767. DOI: 10.1021/acsomega.2c04908.

Anemia Diagnostic System Based on Impedance Measurement of Red Blood Cells.

Cho H, Lee S, Baek Y Sensors (Basel). 2021; 21(23).

PMID: 34884044 PMC: 8659443. DOI: 10.3390/s21238043.

Emerging point-of-care technologies for anemia detection.

An R, Huang Y, Man Y, Valentine R, Kucukal E, Goreke U Lab Chip. 2021; 21(10):1843-1865.

PMID: 33881041 PMC: 8875318. DOI: 10.1039/d0lc01235a.

Microfluidic system for screening disease based on physical properties of blood.

Yadav S, Sikarwar B, Ranjan P, Janardhanan R Bioimpacts. 2020; 10(3):141-150.

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