Emerging Microengineered Tools for Functional Analysis and Phenotyping of Blood Cells

Overview

Journal Trends Biotechnol

Specialty Biochemistry

Date 2014 Oct 7

PMID 25283971

Citations 6

Authors

Xiang Li

Weiqiang Chen

Zida Li

Ling Li

Hongchen Gu

Jianping Fu

Affiliations

Soon will be listed here.

Abstract

The available techniques for assessing blood cell functions are limited considering the various types of blood cell and their diverse functions. In the past decade, rapid advances in microengineering have enabled an array of blood cell functional measurements that are difficult or impossible to achieve using conventional bulk platforms. Such miniaturized blood cell assay platforms also provide the attractive capabilities of reducing chemical consumption, cost, and assay time, as well as exciting opportunities for device integration, automation, and assay standardization. This review summarizes these contemporary microengineered tools and discusses their promising potential for constructing accurate in vitro models and rapid clinical diagnosis using minimal amounts of whole-blood samples.

Citing Articles

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A Miniaturized Hemoretractometer for Blood Clot Retraction Testing.

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