Reproductive Aging and Elective Fertility Preservation

Overview

Journal J Ovarian Res

Publisher Biomed Central

Specialties Gynecology & Obstetrics
Reproductive Medicine

Date 2018 Aug 13

PMID 30098598

Citations 27

Authors

Rani Fritz

Sangita Jindal

Affiliations

Soon will be listed here.

Abstract

Reproductive aging is a natural process that occurs in all women, eventually leading to reproductive senescence and menopause. Over the past half century there has been a trend towards delayed motherhood. Postponing reproduction can increase the chance of a woman remaining involuntarily childless as well as an increase in pregnancy complications in those that do achieve pregnancy at advanced maternal age. Despite the well-documented decrease in fecundity that occurs as a woman ages, reproductive aged women frequently overestimate the age at which a significant decline in fertility occurs and overestimate the success of assisted reproductive technologies (ART) to circumvent infertility. Oocyte cryopreservation enables women to achieve genetically related offspring in the event that they desire to postpone their childbearing to an age after which a significant decline in fertility occurs or in circumstances in which their reproductive potential is compromised due to medical pathology. Available success rates and safety data following oocyte cryopreservation have been reassuring and is not considered experimental according to the American Society for Reproductive Medicine and the European Society for Human Reproduction and Embryology. This review article will focus on an evidence-based discussion relating to reproductive aging and oocyte cryopreservation.

Citing Articles

Determination of Fertility Hormones and Adipokines by LC-MRM/MS Analysis.

Illiano A, Pinto G, Mallardo A, Melchiorre C, Serpico S, Varelli M ACS Omega. 2024; 9(33):35482-35489.

PMID: 39184469 PMC: 11339818. DOI: 10.1021/acsomega.4c02250.

Mapping ethical, legal, and social implications (ELSI) of fertility preservation.

Alon I, Bussod I, Golan O, Ravitsky V J Assist Reprod Genet. 2024; 41(9):2495-2514.

PMID: 39141169 PMC: 11405582. DOI: 10.1007/s10815-024-03210-w.

BCORL1, POF1B, and USP9X copy number variation in women with idiopathic diminished ovarian reserve.

Furtado C, Soares M, Verruma C, de Oliveira Gennaro F, Silva L, Ferriani R J Assist Reprod Genet. 2024; 41(9):2279-2288.

PMID: 38995507 PMC: 11405560. DOI: 10.1007/s10815-024-03185-8.

Machine learning for predicting elective fertility preservation outcomes.

Braude I, Herzberger E, Semo M, Soifer K, Gepstein N, Wiser A Sci Rep. 2024; 14(1):10158.

PMID: 38698132 PMC: 11065881. DOI: 10.1038/s41598-024-60671-w.

Climacteric status at age 46 is associated with poorer work ability, lower 2-year participation in working life, and a higher 7-year disability retirement rate: a Northern Finland Birth Cohort 1966 study.

Saarinen T, Savukoski S, Pesonen P, Vaaramo E, Laitinen J, Varanka-Ruuska T Menopause. 2024; 31(4):275-281.

PMID: 38412401 PMC: 11896111. DOI: 10.1097/GME.0000000000002327.

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