Effect of Nausea and Vomiting on Anxiety and Depression Levels in Early Pregnancy

Overview

Journal Eurasian J Med

Publisher Aves

Specialty General Medicine

Date 2018 Jul 14

PMID 30002578

Citations 8

Authors

Fatma Beyazit

Basak Sahin

Affiliations

Soon will be listed here.

Abstract

Objective: Nausea and vomiting of pregnancy (NVP) have been reported to be associated with distinct physiological responses to psychosocial stress. In this study, we aimed to evaluate the impact of nausea and vomiting on anxiety and depression during pregnancy.

Materials And Methods: Eighty-three pregnant women with nausea and vomiting and 83 healthy pregnant women were included. All participants completed the demography- and pregnancy-related questionnaire, including Rhodes Index of Nausea and Vomiting, Beck Anxiety Inventory (BAI), and Edinburgh Postnatal Depression Scale (EPDS).

Results: The median BAI and EPDS levels were 13 (min-max: 0-43) and 7 (min-max: 0-20) for the study group and 4 (min-max: 0-26) and 4 (min-max: 0-16) for control group, respectively. A univariate analysis revealed a statistically significant increase in terms of BAI levels (p<0.001) between the groups, but no significant difference was observed in terms of EPDS. In a logistic regression analysis, both anxiety (p=0.018) and depression (p=0.022) were found to be affected by NVP. The BAI levels of the NVP group correlated with the severity of NVP.

Conclusion: According to the results of the present study, women with severe NVP experienced a higher level of anxiety and depression, which necessitates an extra awareness from healthcare professionals in order to be able to contribute effectively.

Citing Articles

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References

Beck A, Epstein N, Brown G, Steer R . An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988; 56(6):893-7. DOI: 10.1037//0022-006x.56.6.893. View

Rhodes V, Watson P, Johnson M . Development of reliable and valid measures of nausea and vomiting. Cancer Nurs. 1984; 7(1):33-41. View

McCarthy F, Lutomski J, Greene R . Hyperemesis gravidarum: current perspectives. Int J Womens Health. 2014; 6:719-25. PMC: 4130712. DOI: 10.2147/IJWH.S37685. View

Aksoy H, Yucel B, Aksoy U, Acmaz G, Aydin T, Babayigit M . The relationship between expectation, experience and perception of labour pain: an observational study. Springerplus. 2016; 5(1):1766. PMC: 5056917. DOI: 10.1186/s40064-016-3366-z. View

Fiaschi L, Nelson-Piercy C, Tata L . Hospital admission for hyperemesis gravidarum: a nationwide study of occurrence, reoccurrence and risk factors among 8.2 million pregnancies. Hum Reprod. 2016; 31(8):1675-84. DOI: 10.1093/humrep/dew128. View

Kitamura T, Sugawara M, Sugawara K, Toda M, Shima S . Psychosocial study of depression in early pregnancy. Br J Psychiatry. 1996; 168(6):732-8. DOI: 10.1192/bjp.168.6.732. View

Lee N, Saha S . Nausea and vomiting of pregnancy. Gastroenterol Clin North Am. 2011; 40(2):309-34, vii. PMC: 3676933. DOI: 10.1016/j.gtc.2011.03.009. View

Bergink V, Kooistra L, Lambregtse-van den Berg M, Wijnen H, Bunevicius R, van Baar A . Validation of the Edinburgh Depression Scale during pregnancy. J Psychosom Res. 2011; 70(4):385-9. DOI: 10.1016/j.jpsychores.2010.07.008. View

Cox J, Holden J, Sagovsky R . Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987; 150:782-6. DOI: 10.1192/bjp.150.6.782. View

10.

Hizli D, Kamalak Z, Kosus A, Kosus N, Akkurt G . Hyperemesis gravidarum and depression in pregnancy: is there an association?. J Psychosom Obstet Gynaecol. 2012; 33(4):171-5. DOI: 10.3109/0167482X.2012.717129. View

11.

Aksoy A . Hyperemesis Incidence in Planned versus Unplanned Pregnancy. Eurasian J Med. 2015; 40(2):72-4. PMC: 4261684. View

12.

Jahangiri F, Hirshfeld-Cytron J, Goldman K, Pavone M, Gerber S, Klock S . Correlation between depression, anxiety, and nausea and vomiting during pregnancy in an in vitro fertilization population: a pilot study. J Psychosom Obstet Gynaecol. 2011; 32(3):113-8. DOI: 10.3109/0167482X.2011.576790. View

13.

Roseboom T, Ravelli A, van der Post J, Painter R . Maternal characteristics largely explain poor pregnancy outcome after hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol. 2011; 156(1):56-9. DOI: 10.1016/j.ejogrb.2011.01.010. View

14.

Annagur B, Secilmis Kerimoglu O, Gunduz S, Tazegul A . Are there any differences in psychiatric symptoms and eating attitudes between pregnant women with hyperemesis gravidarum and healthy pregnant women?. J Obstet Gynaecol Res. 2013; 40(4):1009-14. DOI: 10.1111/jog.12274. View

15.

Bai G, Korfage I, Hafkamp-de Groen E, Jaddoe V, Mautner E, Raat H . Associations between Nausea, Vomiting, Fatigue and Health-Related Quality of Life of Women in Early Pregnancy: The Generation R Study. PLoS One. 2016; 11(11):e0166133. PMC: 5096665. DOI: 10.1371/journal.pone.0166133. View

16.

Bozzo P, Einarson T, Koren G, Einarson A . Nausea and vomiting of pregnancy (NVP) and depression: cause or effect?. Clin Invest Med. 2011; 34(4):E245. DOI: 10.25011/cim.v34i4.15367. View

17.

Tsang I, Katz V, Wells S . Maternal and fetal outcomes in hyperemesis gravidarum. Int J Gynaecol Obstet. 1996; 55(3):231-5. DOI: 10.1016/s0020-7292(96)02778-6. View

18.

Simsek Y, Celik O, Yilmaz E, Karaer A, Yildirim E, Yologlu S . Assessment of anxiety and depression levels of pregnant women with hyperemesis gravidarum in a case-control study. J Turk Ger Gynecol Assoc. 2014; 13(1):32-6. PMC: 3940221. DOI: 10.5152/jtgga.2012.01. View

19.

Nazik E, Eryilmaz G . Incidence of pregnancy-related discomforts and management approaches to relieve them among pregnant women. J Clin Nurs. 2013; 23(11-12):1736-50. DOI: 10.1111/jocn.12323. View

20.

Heitmann K, Nordeng H, Havnen G, Solheimsnes A, Holst L . The burden of nausea and vomiting during pregnancy: severe impacts on quality of life, daily life functioning and willingness to become pregnant again - results from a cross-sectional study. BMC Pregnancy Childbirth. 2017; 17(1):75. PMC: 5329925. DOI: 10.1186/s12884-017-1249-0. View