Association Between Nausea and Vomiting During Pregnancy and Sleep Quality: Mediating Effect of Depressive Symptoms

Overview

Journal Int J Gen Med

Publisher Dove Medical Press

Specialty General Medicine

Date 2021 Jan 15

PMID 33447075

Citations 3

Authors

Pengsheng Li

Haiyan Wang

Gengdong Chen

Jinping Feng

Dazhi Fan

Dongxin Lin

Jiaming Rao

Zixing Zhou

Zhengping Liu

Xiaoling Guo

Affiliations

Soon will be listed here.

Abstract

Purpose: Nausea and vomiting during pregnancy (NVP) of varying degrees of severity are commonly experienced by pregnant women. This paper explores the association between NVP and poor sleep quality.

Patients And Methods: A cross-sectional study was conducted in an obstetrics clinic. A total of 2494 pregnant women (representing a response rate of 92.7%) completed a self-administered questionnaire.

Results: Of the 2494 participants, the mean sleep duration was 7.76 hours, and 54.3% of them report poor sleep quality (ie, a Pittsburgh Sleep Quality Index global score > 5). In this study, 49.1%, 49.3% and 1.6% women reported mild, moderate, and severe NVP, respectively. Compare with women with mild NVP, women with moderate or severe NVP were more likely to report poor sleep quality ( = 30.16, < 0.001). After adjusted for demographics and gestational age, moderate and severe NVP were associated with poor sleep quality (adjusted odds ratio (AOR) = 1.66, 95% confidence interval (CI) = 1.40-1.96, and AOR = 2.95, 95% CI = 1.44-6.02, respectively). Moreover, depressive symptoms mediated the association between NVP and poor sleep quality (β = 0.060, = 0.033, 95% CI = 0.028-0.180).

Conclusion: Our study suggested that moderate and severe NVP increase the risk of poor sleep quality. Further studies are warranted that focus on the mechanisms of the association between NVP and poor sleep quality.

Citing Articles

Sleep quality disparities in different pregnancy trimesters in low- and middle-income countries: a systematic review and meta-analysis.

Mislu E, Kumsa H, Tadesse S, Arage M, Susu B, Ayele M BMC Pregnancy Childbirth. 2024; 24(1):627.

PMID: 39354392 PMC: 11446071. DOI: 10.1186/s12884-024-06830-3.

Influencing factors of sleep quality in pregnant: a structural equation model approach.

Bahani M, Zhang Y, Guo Y, Haretebieke S, Wu D, Zhang L BMC Psychol. 2024; 12(1):171.

PMID: 38528622 PMC: 10964610. DOI: 10.1186/s40359-024-01657-1.

Quality of life in Norwegian pregnant women and men with pregnant partners, and association with perception of sleep and depressive symptoms: a cross-sectional study.

Brekke M, Amro A, Smastuen M, Glavin K, Solberg B, Oygarden A BMC Pregnancy Childbirth. 2023; 23(1):37.

PMID: 36653752 PMC: 9847178. DOI: 10.1186/s12884-023-05379-x.

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