» Articles » PMID: 29973994

Effect of Infection on Serum Lipid Profile

Overview
Journal J Lipids
Publisher Wiley
Date 2018 Jul 6
PMID 29973994
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Some studies suggest a significant relationship between infection and atherogenesis; but the mechanism of the relationship is almost unknown. The current study aimed at evaluating the relationship between infection and serum lipid profile.

Patients And Methods: The current study was conducted on 2573 patients, from 2008 to 2015. The serum anti- antibody titer and serum lipid profile were assessed in the study population; data were statistically analyzed by SPSS version 16. values < 0.05 were considered significant.

Results: In the current study, 66.5% of the cases were serologically positive for . Among male cases, the level of low density lipoprotein (LDL) was higher in patients with infection, compared with that of the ones without the infection ( = 0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in the cases with infection; there was no statistically significant difference between the cases with and without infection regarding the level of HDL and TG. Among female cases, the level of TG was significantly lower in patients with infection, compared with that of the ones without the infection ( = 0.001); but there was no significant difference between the cases with and without infection regarding the level of LDL and HDL. The mean fasting blood sugar (FBS) in the cases with infection was significantly higher than that of the ones without the infection ( = 0.04).

Conclusion: According to the results of the current study, the levels of LDL and FBS were high among the male cases with infection. However, in females with infection the level of TG was low; hence, it seems that the atherogenicity of affected the level of blood sugar more.

Citing Articles

Association of triglyceride-glucose index with helicobacter pylori infection and mortality among the US population.

Zhu X, Xiong Y, Meng X, Xu H, Huo L, Deng W Diabetol Metab Syndr. 2024; 16(1):187.

PMID: 39090745 PMC: 11293276. DOI: 10.1186/s13098-024-01422-9.


Helicobacter pylori components increase the severity of metabolic syndrome and its hepatic manifestations induced by a high fat diet.

Tomaszewska A, Gonciarz W, Rechcinski T, Chmiela M, Kurdowska A, Krupa A Sci Rep. 2024; 14(1):5764.

PMID: 38459219 PMC: 10923818. DOI: 10.1038/s41598-024-56308-7.


() Infection-Associated Dyslipidemia in the Asir Region of Saudi Arabia.

Izhari M, Al Mutawa O, Mahzari A, Alotaibi E, Almashary M, Alshahrani J Life (Basel). 2023; 13(11).

PMID: 38004346 PMC: 10672336. DOI: 10.3390/life13112206.


infection increases the risk of carotid plaque formation: Clinical samples combined with bioinformatics analysis.

Chen Y, You N, Yang C, Zhang J Heliyon. 2023; 9(9):e20037.

PMID: 37809782 PMC: 10559771. DOI: 10.1016/j.heliyon.2023.e20037.


Effect of Helicobacter pylori eradication on metabolic profile: an international, multicenter, case-control study.

Alavinejad P, Hajiani E, Parsi A, Satari A, Rezaei M, Nayebi M BMC Gastroenterol. 2022; 22(1):507.

PMID: 36482315 PMC: 9733255. DOI: 10.1186/s12876-022-02604-3.


References
1.
Hoffmeister A, Rothenbacher D, Bode G, Persson K, Marz W, Nauck M . Current infection with Helicobacter pylori, but not seropositivity to Chlamydia pneumoniae or cytomegalovirus, is associated with an atherogenic, modified lipid profile. Arterioscler Thromb Vasc Biol. 2001; 21(3):427-32. DOI: 10.1161/01.atv.21.3.427. View

2.
Zhu J, Quyyumi A, Muhlestein J, Nieto F, Horne B, Zalles-Ganley A . Lack of association of Helicobacter pylori infection with coronary artery disease and frequency of acute myocardial infarction or death. Am J Cardiol. 2002; 89(2):155-8. DOI: 10.1016/s0002-9149(01)02192-0. View

3.
Kim H, Jeon H, Park I, Choi J, Kang J, Min K . Helicobacter pylori infection is associated with elevated low density lipoprotein cholesterol levels in elderly Koreans. J Korean Med Sci. 2011; 26(5):654-8. PMC: 3082118. DOI: 10.3346/jkms.2011.26.5.654. View

4.
Cullen P, Assmann G . High risk strategies for atherosclerosis. Clin Chim Acta. 1999; 286(1-2):31-45. DOI: 10.1016/s0009-8981(99)00092-3. View

5.
Vafaeimanesh J, Parham M, Seyyedmajidi M, Bagherzadeh M . Helicobacter pylori infection and insulin resistance in diabetic and nondiabetic population. ScientificWorldJournal. 2014; 2014():391250. PMC: 4227459. DOI: 10.1155/2014/391250. View