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Prognostic Potential of the Panfungal Marker (1 → 3)-β-D-Glucan in Invasive Mycoses Patients

Overview
Journal Mycopathologia
Specialties Microbiology
Pharmacology
Date 2018 Jul 4
PMID 29967970
Citations 3
Authors
P Pini
C Venturelli
M Girardis
F Forghieri
E Blasi
Affiliations
Soon will be listed here.
Abstract

We analyze the prognostic potential of (1 → 3)-β-D-glucan (BG) levels in predicting clinical outcomes in patients with invasive fungal infections, on a population undergoing 253 episodes (177 with positive and 76 with negative outcome). Using linear regression analysis, we assessed the prognostic potential of kinetically evaluated BG levels and we found an overall sensitivity and specificity of 68 and 82%, respectively. Moreover, using an interpretative algorithm based on two distinct cutoff values, we were able to predict the outcome in 84% of the studied population with a diagnostic accuracy of 82%.

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