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Guidelines for the Management of Osteoporosis and Fragility Fractures

Abstract

The purpose of this document, a result of the harmonisation and revision of Guidelines published separately by the SIMFER, SIOMMMS/SIR, and SIOT associations, is to provide practical indications based on specific levels of evidence and various grades of recommendations, drawn from available literature, for the management of osteoporosis and for the diagnosis, prevention, and treatment of fragility fractures. These indications were discussed and formally approved by the delegates of the Italian Scientific Associations involved in the project (SIE, SIGG, SIMFER, SIMG, SIMI, SIOMMMS, SIR, and SIOT).

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References
1.
Lapi F, Simonetti M, Michieli R, Pasqua A, Brandi M, Frediani B . Assessing 5-year incidence rates and determinants of osteoporotic fractures in primary care. Bone. 2011; 50(1):85-90. DOI: 10.1016/j.bone.2011.09.048. View

2.
Gillespie W, Gillespie L, Parker M . Hip protectors for preventing hip fractures in older people. Cochrane Database Syst Rev. 2010; (10):CD001255. DOI: 10.1002/14651858.CD001255.pub4. View

3.
Ganda K, Puech M, Chen J, Speerin R, Bleasel J, Center J . Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int. 2012; 24(2):393-406. DOI: 10.1007/s00198-012-2090-y. View

4.
Rizzoli R, Biver E . Glucocorticoid-induced osteoporosis: who to treat with what agent?. Nat Rev Rheumatol. 2014; 11(2):98-109. DOI: 10.1038/nrrheum.2014.188. View

5.
Rossini M, Adami S, Viapiana O, Fracassi E, Idolazzi L, Povino M . Dose-dependent short-term effects of single high doses of oral vitamin D(3) on bone turnover markers. Calcif Tissue Int. 2012; 91(6):365-9. DOI: 10.1007/s00223-012-9637-y. View