PREVALENCE AND RISK FACTORS OF HYPERKALEMIA AFTER LIVER TRANSPLANTATION

Overview

Journal Arq Bras Cir Dig

Specialties Gastroenterology
General Surgery

Date 2018 Jun 28

PMID 29947691

Citations 3

Authors

Helem Sena Ribeiro

Michelle Carvalho Oliveira

Lucilene Rezende Anastacio

Simone Vasconcelos Generoso

Agnaldo Soares Lima

Maria Isabel Correia

Affiliations

Soon will be listed here.

Abstract

Background: There is a lack of data regarding hyperkalemia after liver transplantation.

Aim: To evaluate the prevalence of hyperkalemia after liver transplantation and its associated factors.

Methods: This retrospective cohort study evaluated 147 consecutive post-transplant patients who had at least one year of outpatient medical follow up. The data collection included gender, age, potassium values, urea, creatinine, sodium and medication use at 1, 6 and 12 months after. Hyperkalemia was defined as serum potassium concentrations higher than 5.5 mEq/l.

Results: Hiperkalemia was observed in 18.4%, 17.0% and 6.1% of patients 1, 6 and 12 months after tranplantation, respectively. Older age (p=0.021), low creatinine clearance (p=0.007), increased urea (p=0.010) and hypernatremia (p=0.014) were factors associated with hyperkalemia, as well as the dose of prednisone at six months (p=0.014).

Conclusion: Hyperkalemia was prevalent in less than 20% of patients in the 1st month after liver transplantation and decreased over time. Considering that hyperkalemia does not affect all patients, attention should be paid to the routine potassium intake recommendations, and treatment should be individualized.

Citing Articles

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RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT.

Freitas A, Coelho J, Watanabe M, Lima R Arq Bras Cir Dig. 2020; 33(1):e1499.

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