Surface Marker Characterization of EBV Target Cells in Normal Blood and Tonsil B Lymphocyte Populations

Overview

Journal J Immunol

Specialty Allergy & Immunology

Date 1985 Oct 1

PMID 2993411

Citations 9

Authors

P Aman

J Gordon

N Lewin

M Nordstrom

G Klein

A Carstensson

Affiliations

Soon will be listed here.

Abstract

Human FACS-sorted B lymphocyte subpopulations were investigated for their susceptibility to immortalization by Epstein Barr virus (EBV). Only B cells reacting with the monoclonal antibody B2 were immortalized, whereas cells reacting with anti-human IgG or the monoclonal antibody BB2 were not responding. Cells positive or negative for IgM, IgD, Burkitt's lymphoma antigen (BLA), BB1, and HB2 were all transformed by EBV.

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