Abundant Heterotopic Bone Formation Following Use of RhBMP-2 in the Treatment of Acetabular Bone Defects During Revision Hip Arthroplasty

Overview

Journal Arthroplast Today

Publisher Elsevier

Date 2018 Jun 14

PMID 29896546

Citations 3

Authors

Alexander Arzeno

Tim Wang

James I Huddleston 3rd

Affiliations

Soon will be listed here.

Abstract

Revision hip arthroplasty in the setting of periacetabular bone loss presents a significant challenge, as options for restoring bone loss are limited. Recombinant human bone morphogenetic protein-2 may offer a solution by promoting bone growth to restore bone stock before implant reimplantation. Here we present a case of a patient with a periprosthetic acetabulum fracture, resulting in pelvic discontinuity as the result of significant periacetabular bone loss. Using a staged approach, periacetabular bone stock was nearly entirely reconstituted using recombinant BMPs and allograft, which resulted in stable fixation, but with abundant heterotopic bone formation. Recombinant BMP-2 offers a useful tool for restoring bone stock in complex hip arthroplasty revision cases with periacetabular bone loss; however, caution must be used as overabundant bone growth as heterotopic ossification may result.

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