Roles of Host Immunity in Viral Myocarditis and Dilated Cardiomyopathy

Overview

Journal J Immunol Res

Publisher Wiley

Specialty Allergy & Immunology

Date 2018 Jun 2

PMID 29854842

Citations 19

Authors

Lifang Zhao

Zhaoying Fu

Affiliations

Soon will be listed here.

Abstract

The pathogenesis of viral myocarditis includes both the direct damage mediated by viral infection and the indirect lesion resulted from host immune responses. Myocarditis can progress into dilated cardiomyopathy that is also associated with immunopathogenesis. T cell-mediated autoimmunity, antibody-mediated autoimmunity (autoantibodies), and innate immunity, working together, contribute to the development of myocarditis and dilated cardiomyopathy.

Citing Articles

Integrated Metabolomics and Proteomics Analysis of the Myocardium in a Mouse Model of Acute Viral Myocarditis.

Xue Y, Zhang J, Chen M, Fan Q, Huang T, Ke J Immun Inflamm Dis. 2025; 13(2):e70151.

PMID: 39912544 PMC: 11800238. DOI: 10.1002/iid3.70151.

Advances in the mechanism of inflammasomes activation in herpes virus infection.

Chen H, Jian Z, Xu T, Xu L, Deng L, Shao L Front Immunol. 2024; 15:1346878.

PMID: 38590522 PMC: 10999540. DOI: 10.3389/fimmu.2024.1346878.

Construction and evaluation of immune-related diagnostic model in patients with heart failure caused by idiopathic dilated cardiomyopathy.

Xu S, Wu Z, Chen H BMC Cardiovasc Disord. 2024; 24(1):92.

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Integrating scRNA-seq to explore novel macrophage infiltration-associated biomarkers for diagnosis of heart failure.

Li S, Ge T, Xu X, Xie L, Song S, Li R BMC Cardiovasc Disord. 2023; 23(1):560.

PMID: 37974098 PMC: 10652463. DOI: 10.1186/s12872-023-03593-1.

ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis.

Yang P, Li F, Tang J, Tian Q, Zheng Z PeerJ. 2023; 11:e16320.

PMID: 37901475 PMC: 10607261. DOI: 10.7717/peerj.16320.

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