» Articles » PMID: 29728899

Stereotactically Navigated Percutaneous Microwave Ablation (MWA) Compared to Conventional MWA: a Matched Pair Analysis

Overview
Publisher Springer
Date 2018 May 6
PMID 29728899
Citations 14
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: To compare CT-navigated stereotactic microwave ablation (SMWA) to non-navigated conventional MWA (CMWA) for percutaneous ablation of liver malignancies.

Methods: A matched pair analysis of 36 patients who underwent MWA of primary or secondary liver malignancies (10 hepatocellular carcinoma and 8 metastases) was conducted. A total of 18 patients undergoing SMWA were included in this prospective study. Patients were matched in terms of tumor size, liver segment and entity to retrospective CMWA procedures. The endpoints were procedure time, accuracy of needle placement, technical success rate, complication rate and dose-length product (DLP).

Results: The procedure durations were 23.9 min (SD 3.7) for CMWA and 21.8 min (SD 16.3) for SMWA (p = 0.22). The procedural accuracy for SMWA and CMWA was identical for both groups (3.7 mm). The total DLP was significantly lower for SMWA than for CMWA (2115 mGy cm (SD 276) vs. 3109 mGy cm (SD 1137), respectively; p < 0.01). Complete ablation without residual tumor was observed in 94% (17 of 18) of SMWA and in 83% (15 of 18) of CMWA patients (p = 0.31). No complications occurred.

Conclusions: SMWA is highly accurate and reduces the radiation dose without increasing the procedure time.

Citing Articles

Stereotactic Percutaneous Electrochemotherapy as a New Minimal Invasive Treatment Modality for Primary and Secondary Liver Malignancies.

Luerken L, Goetz A, Mayr V, Zhang L, Schlitt A, Haimerl M Biomedicines. 2025; 12(12.

PMID: 39767776 PMC: 11673152. DOI: 10.3390/biomedicines12122870.


The Efficacy and Safety of a Microwave Ablation System with a Dipole Antenna Design Featuring Floating Sleeves and Anti-Phase Technology in Stereotactic Percutaneous Liver Tumor Ablation: Results from a Prospective Study.

Zhang L, Luerken L, Mayr V, Goetz A, Schlitt A, Stroszczynski C Cancers (Basel). 2025; 16(24.

PMID: 39766112 PMC: 11674554. DOI: 10.3390/cancers16244211.


Feasibility of stereotactic optical navigation for needle positioning in percutaneous nephrolithotomy.

Spenkelink I, Zhu X, Futterer J, Langenhuijsen J World J Urol. 2024; 42(1):181.

PMID: 38507097 PMC: 10954992. DOI: 10.1007/s00345-024-04870-0.


Ablative and non-surgical therapies for early and very early hepatocellular carcinoma: a systematic review and network meta-analysis.

Wade R, South E, Anwer S, Sharif-Hurst S, Harden M, Fulbright H Health Technol Assess. 2023; 27(29):1-172.

PMID: 38149643 PMC: 11017143. DOI: 10.3310/GK5221.


Ablation margin quantification after thermal ablation of malignant liver tumors: How to optimize the procedure? A systematic review of the available evidence.

Hendriks P, Boel F, Oosterveer T, Broersen A, de Geus-Oei L, Dijkstra J Eur J Radiol Open. 2023; 11:100501.

PMID: 37405153 PMC: 10316004. DOI: 10.1016/j.ejro.2023.100501.


References
1.
Abdullah B, Yeong C, Goh K, Yoong B, Ho G, Yim C . Robotic-assisted thermal ablation of liver tumours. Eur Radiol. 2014; 25(1):246-57. DOI: 10.1007/s00330-014-3391-7. View

2.
Solomon S, Patriciu A, Bohlman M, Kavoussi L, Stoianovici D . Robotically driven interventions: a method of using CT fluoroscopy without radiation exposure to the physician. Radiology. 2002; 225(1):277-82. PMC: 3107539. DOI: 10.1148/radiol.2251011133. View

3.
Lubner M, Brace C, Hinshaw J, Lee Jr F . Microwave tumor ablation: mechanism of action, clinical results, and devices. J Vasc Interv Radiol. 2010; 21(8 Suppl):S192-203. PMC: 3065977. DOI: 10.1016/j.jvir.2010.04.007. View

4.
Engstrand J, Toporek G, Harbut P, Jonas E, Nilsson H, Freedman J . Stereotactic CT-Guided Percutaneous Microwave Ablation of Liver Tumors With the Use of High-Frequency Jet Ventilation: An Accuracy and Procedural Safety Study. AJR Am J Roentgenol. 2016; 208(1):193-200. DOI: 10.2214/AJR.15.15803. View

5.
Kokudo N, Hasegawa K, Akahane M, Igaki H, Izumi N, Ichida T . Evidence-based Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2013 update (3rd JSH-HCC Guidelines). Hepatol Res. 2015; 45(2). DOI: 10.1111/hepr.12464. View