» Articles » PMID: 29693559

A Novel Approach to the Identification of Compromised Pulmonary Systems in Smokers by Exploiting Tidal Breathing Patterns

Overview
Journal Sensors (Basel)
Publisher MDPI
Specialty Biotechnology
Date 2018 Apr 26
PMID 29693559
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

Smoking causes unalterable physiological abnormalities in the pulmonary system. This is emerging as a serious threat worldwide. Unlike spirometry, tidal breathing does not require subjects to undergo forceful breathing maneuvers and is progressing as a new direction towards pulmonary health assessment. The aim of the paper is to evaluate whether tidal breathing signatures can indicate deteriorating adult lung condition in an otherwise healthy person. If successful, such a system can be used as a pre-screening tool for all people before some of them need to undergo a thorough clinical checkup. This work presents a novel systematic approach to identify compromised pulmonary systems in smokers from acquired tidal breathing patterns. Tidal breathing patterns are acquired during restful breathing of adult participants. Thereafter, physiological attributes are extracted from the acquired tidal breathing signals. Finally, a unique classification approach of locally weighted learning with ridge regression (LWL-ridge) is implemented, which handles the subjective variations in tidal breathing data without performing feature normalization. The LWL-ridge classifier recognized compromised pulmonary systems in smokers with an average classification accuracy of 86.17% along with a sensitivity of 80% and a specificity of 92%. The implemented approach outperformed other variants of LWL as well as other standard classifiers and generated comparable results when applied on an external cohort. This end-to-end automated system is suitable for pre-screening people routinely for early detection of lung ailments as a preventive measure in an infrastructure-agnostic way.

Citing Articles

Cigarette Smoking Detection with An Inertial Sensor and A Smart Lighter.

Senyurek V, Imtiaz M, Belsare P, Tiffany S, Sazonov E Sensors (Basel). 2019; 19(3).

PMID: 30700056 PMC: 6387353. DOI: 10.3390/s19030570.

References
1.
van der Ent C, Brackel H, van der Laag J, Bogaard J . Tidal breathing analysis as a measure of airway obstruction in children three years of age and older. Am J Respir Crit Care Med. 1996; 153(4 Pt 1):1253-8. DOI: 10.1164/ajrccm.153.4.8616550. View

2.
Milic-Emili J . Does mechanical injury of the peripheral airways play a role in the genesis of COPD in smokers?. COPD. 2006; 1(1):85-92. DOI: 10.1081/COPD-120028700. View

3.
Colasanti R, Morris M, Madgwick R, Sutton L, Williams E . Analysis of tidal breathing profiles in cystic fibrosis and COPD. Chest. 2004; 125(3):901-8. DOI: 10.1378/chest.125.3.901. View

4.
Pearsall M, Feldman J . When does apparatus dead space matter for the pediatric patient?. Anesth Analg. 2014; 118(4):776-80. DOI: 10.1213/ANE.0000000000000148. View

5.
Sancho J, Servera E, Diaz J, Marin J . Comparison of peak cough flows measured by pneumotachograph and a portable peak flow meter. Am J Phys Med Rehabil. 2004; 83(8):608-12. DOI: 10.1097/01.phm.0000133431.70907.a2. View