Design Strategies for Physical-stimuli-responsive Programmable Nanotherapeutics

Overview

Journal Drug Discov Today

Specialty Pharmacology

Date 2018 Apr 14

PMID 29653291

Citations 19

Authors

Fitsum Feleke Sahle

Muhammad Gulfam

Tao L Lowe

Affiliations

Soon will be listed here.

Abstract

Nanomaterials that respond to externally applied physical stimuli such as temperature, light, ultrasound, magnetic field and electric field have shown great potential for controlled and targeted delivery of therapeutic agents. However, the body of literature on programming these stimuli-responsive nanomaterials to attain the desired level of pharmacologic responses is still fragmented and has not been systematically reviewed. The purpose of this review is to summarize and synthesize the literature on various design strategies for simple and sophisticated programmable physical-stimuli-responsive nanotherapeutics.

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