Samter's Triad: State of the Art

Overview

Journal Clin Exp Otorhinolaryngol

Date 2018 Apr 13

PMID 29642688

Citations 13

Authors

Sung-Dong Kim

Kyu-Sup Cho

Affiliations

Soon will be listed here.

Abstract

Samter's triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST. As concern for ST increase, more application of aspirin desensitization will be required to manage this disease successfully. There is also a need for continued research efforts in pathophysiology, treatment, and possible prevention.

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