Biophysical Properties of Extracellular Matrix: Linking Obesity and Cancer

Overview

Journal Trends Cancer

Publisher Cell Press

Specialty Oncology

Date 2018 Apr 3

PMID 29606310

Citations 22

Authors

Joseph E Druso

Claudia Fischbach

Affiliations

Soon will be listed here.

Abstract

Obesity has been associated with increased severity of diagnoses for several types of cancer, and recent evidence suggests that the mechanism by which obese tissues contribute to cancer progression involves the extracellular matrix (ECM). Understanding the physicochemical differences between lean and obese ECM, and how cancer cells respond to these differences, promises therapeutic insight.

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