Current Role of Standardized Uptake Value-derived Ratios in N2 Fluorine-18 Fluorodeoxyglucose Positron-emission Tomography Non-small Cell Lung Cancer
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Mediastinal staging is a crucial moment in management of non-small cell lung cancer (NSCLC) patients. In integrated pathways, 18-fluorine fluorodeoxyglucose positron-emission tomography (F-FDG-PET/CT) is an indispensable imaging resource with its peculiarities and its limitations. A critical review of work up protocols would certainly help to standardize procedures with important reflections also on the diagnostic value of this examination. In this regard, new semi-quantitative and semi-qualitative indexes have been proposed with the aim of increasing the accuracy of F-FDG-PET/CT in mediastinal lymph node staging. These latter, such as SUV and SUV indexes, seem to overcome the problem of spatial resolution and discrimination of malignancy by endorsing a new predictive and prognostic role.
The lung cancers: staging and response, CT, F-FDG PET/CT, MRI, DWI: review and new perspectives.
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