Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2018 Mar 30

PMID 29593649

Citations 33

Authors

Daniel Garcia de la Serrana

Daniel J Macqueen

Affiliations

Soon will be listed here.

Abstract

The insulin-like growth factor (Igf) binding protein (Igfbp) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the Igfbps of teleost fishes, where genome duplication events have diversified gene repertoire, function, and physiological regulation-with six core Igfbps expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost Igfbp evolution, function, and expression-level regulation, we highlight gaps in our understanding and promising areas for future work.

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