The New Low-Profile WEB 17 System for Treatment of Intracranial Aneurysms: First Clinical Experiences

Overview

Journal AJNR Am J Neuroradiol

Specialty Neurology

Date 2018 Mar 24

PMID 29567650

Citations 26

Authors

S B T van Rooij

J P Peluso

M Sluzewski

H G Kortman

W J van Rooij

Affiliations

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Abstract

Background And Purpose: The Woven EndoBridge (WEB) is an intrasaccular flow diverter intended to treat wide-neck aneurysms. The latest generation WEBs needed a 0.021-inch microcatheter in the small sizes. Recently, a lower profile range of WEBs compliant with a 0.017-inch microcatheter (WEB 17) has been introduced. We present the first clinical results of treatment of both ruptured and unruptured aneurysms with the WEB 17.

Materials And Methods: Between December 2016 and September 2017, forty-six aneurysms in 40 patients were treated with the WEB 17. No supporting stents or balloons were used. Twenty-five aneurysms were ruptured (54%). There were 6 men and 34 women (mean age, 62 years; median, 63 years; range, 46-87 years). The mean aneurysm size was 4.9 mm (median, 5 mm; range, 2-7 mm).

Results: There were 2 thromboembolic procedural complications without clinical sequelae and no ruptures. The overall permanent procedural complication rate was 0% (0 of 40; 97.5% CI, 0%-10.4%). Imaging follow-up at 3 months was available in 33 patients with 39 aneurysms (97.5% of 40 eligible aneurysms). In 1 aneurysm, the detached WEB was undersized and the remnant was additionally treated with coils after 1 week. This same aneurysm reopened at 3 months and was again treated with a second WEB. One other aneurysm showed persistent WEB filling at 3 months. Complete occlusion was achieved in 28 of 39 aneurysms (72%), and 9 aneurysms (23%) showed a neck remnant.

Conclusions: The WEB 17 is safe and effective for both ruptured and unruptured aneurysms. The WEB 17 is a valuable addition to the existing WEB size range, especially for very small aneurysms.

Citing Articles

Woven EndoBridge 17 device for intracranial aneurysms: A systematic review and meta-analysis.

Rodriguez-Calienes A, Castillo-Huerta N, Vivanco-Suarez J, Vilca-Salas M, Bustamante-Paytan D, Borjas-Calderon N Neuroradiol J. 2025; :19714009251317505.

PMID: 39873452 PMC: 11775924. DOI: 10.1177/19714009251317505.

Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review.

Shao M, White T, Bassett J, Dowlati E, Mehta S, Werner C J Clin Med. 2024; 13(20).

PMID: 39458111 PMC: 11508718. DOI: 10.3390/jcm13206162.

Endovascular Treatment of Bifurcation Aneurysms with the Woven EndoBridge: Product Features and Selected Results of Off-Label Use.

Teranishi K, Ikemura R, Arai S, Mitome-Mishima Y, Kitamura T, Kondo A J Neuroendovasc Ther. 2024; 18(3):65-74.

PMID: 38559453 PMC: 10973567. DOI: 10.5797/jnet.ra.2023-0086.

Safety and efficacy of the Woven Endo-Bridge-17 device for intracranial aneurysm treatment: A systematic review and meta-analysis.

Ghozy S, Motawei A, Moussalem C, Elrefaei A, Kobeissi H, Abbas A Interv Neuroradiol. 2024; :15910199231226294.

PMID: 38234203 PMC: 11569744. DOI: 10.1177/15910199231226294.

CLinical EValuation of WEB 17 device in intracranial aneuRysms (CLEVER): procedural, 30-day and 1-year safety results for ruptured and unruptured aneurysms.

Spelle L, Costalat V, Caroff J, Wodarg F, Fischer S, Herbreteau D J Neurointerv Surg. 2023; 16(12):1299-1306.

PMID: 37914392 PMC: 11671992. DOI: 10.1136/jnis-2023-020866.

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