Stomach-brain Synchrony Reveals a Novel, Delayed-connectivity Resting-state Network in Humans

Overview

Journal Elife

Specialty Biology

Date 2018 Mar 22

PMID 29561263

Citations 62

Authors

Ignacio Rebollo

Anne-Dominique Devauchelle

Benoit Beranger

Catherine Tallon-Baudry

Affiliations

Soon will be listed here.

Abstract

Resting-state networks offer a unique window into the brain's functional architecture, but their characterization remains limited to instantaneous connectivity thus far. Here, we describe a novel resting-state network based on the delayed connectivity between the brain and the slow electrical rhythm (0.05 Hz) generated in the stomach. The gastric network cuts across classical resting-state networks with partial overlap with autonomic regulation areas. This network is composed of regions with convergent functional properties involved in mapping bodily space through touch, action or vision, as well as mapping external space in bodily coordinates. The network is characterized by a precise temporal sequence of activations within a gastric cycle, beginning with somato-motor cortices and ending with the extrastriate body area and dorsal precuneus. Our results demonstrate that canonical resting-state networks based on instantaneous connectivity represent only one of the possible partitions of the brain into coherent networks based on temporal dynamics.

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