High Resolution Human Corneal Imaging Using Full-field Optical Coherence Tomography

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2018 Mar 20

PMID 29552393

Citations 40

Authors

Viacheslav Mazlin

Peng Xiao

Eugenie Dalimier

Kate Grieve

Kristina Irsch

Jose-Alain Sahel

Mathias Fink

A Claude Boccara

Affiliations

Soon will be listed here.

Abstract

We present the first full-field optical coherence tomography (FFOCT) device capable of imaging of the human cornea. We obtained images of the epithelial structures, Bowman's layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemet's membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 µm and relatively large field-of-view of 1.26 mm x 1.26 mm - a combination, which, to the best of our knowledge, has not been possible with other human eye imaging methods. The latter together with a contactless operation, make FFOCT a promising candidate for becoming a new tool in ophthalmic diagnostics.

Citing Articles

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