Safety of Pseudomonas Chlororaphis As a Gene Source for Genetically Modified Crops

Overview

Journal Transgenic Res

Specialty Molecular Biology

Date 2018 Feb 11

PMID 29427161

Citations 15

Authors

Jennifer A Anderson

Jamie Staley

Mary Challender

Jamie Heuton

Affiliations

Soon will be listed here.

Abstract

Genetically modified crops undergo extensive evaluation to characterize their food, feed and environmental safety prior to commercial introduction, using a well-established, science-based assessment framework. One component of the safety assessment includes an evaluation of each introduced trait, including its source organism, for potential adverse pathogenic, toxic and allergenic effects. Several Pseudomonas species have a history of safe use in agriculture and certain species represent a source of genes with insecticidal properties. The ipd072Aa gene from P. chlororaphis encodes the IPD072Aa protein, which confers protection against certain coleopteran pests when expressed in maize plants. P. chlororaphis is ubiquitous in the environment, lacks known toxic or allergenic properties, and has a history of safe use in agriculture and in food and feed crops. This information supports, in part, the safety assessment of potential traits, such as IPD072Aa, that are derived from this source organism.

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