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Novel Highly Pathogenic Avian Influenza A(H5N6) Virus in the Netherlands, December 2017

Overview
Journal Emerg Infect Dis
Specialty Infectious Diseases
Date 2018 Jan 31
PMID 29381134
Citations 38
Authors
Nancy Beerens
Guus Koch
Rene Heutink
Frank Harders
D P Edwin Vries
Cynthia Ho
Alex Bossers
Armin Elbers
Affiliations
Soon will be listed here.
Abstract

A novel highly pathogenic avian influenza A(H5N6) virus affecting wild birds and commercial poultry was detected in the Netherlands in December 2017. Phylogenetic analysis demonstrated that the virus is a reassortant of H5N8 clade 2.3.4.4 viruses and not related to the Asian H5N6 viruses that caused human infections.

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References
1.
Bouwstra R, Heutink R, Bossers A, Harders F, Koch G, Elbers A . Full-Genome Sequence of Influenza A(H5N8) Virus in Poultry Linked to Sequences of Strains from Asia, the Netherlands, 2014. Emerg Infect Dis. 2015; 21(5):872-4. PMC: 4414092. DOI: 10.3201/eid2105.141839. View
2.
Bouwstra R, Koch G, Heutink R, Harders F, van der Spek A, Elbers A . Phylogenetic analysis of highly pathogenic avian influenza A(H5N8) virus outbreak strains provides evidence for four separate introductions and one between-poultry farm transmission in the Netherlands, November 2014. Euro Surveill. 2015; 20(26). DOI: 10.2807/1560-7917.es2015.20.26.21174. View
3.
Lee D, Bertran K, Kwon J, Swayne D . Evolution, global spread, and pathogenicity of highly pathogenic avian influenza H5Nx clade 2.3.4.4. J Vet Sci. 2017; 18(S1):269-280. PMC: 5583414. DOI: 10.4142/jvs.2017.18.S1.269. View
4.
Slomka M, Pavlidis T, Banks J, Shell W, McNally A, Essen S . Validated H5 Eurasian real-time reverse transcriptase-polymerase chain reaction and its application in H5N1 outbreaks in 2005-2006. Avian Dis. 2007; 51(1 Suppl):373-7. DOI: 10.1637/7664-060906R1.1. View
5.
Xu X, Subbarao , Cox N, Guo Y . Genetic characterization of the pathogenic influenza A/Goose/Guangdong/1/96 (H5N1) virus: similarity of its hemagglutinin gene to those of H5N1 viruses from the 1997 outbreaks in Hong Kong. Virology. 1999; 261(1):15-9. DOI: 10.1006/viro.1999.9820. View