Physical Exosome:exosome Interactions

Overview

Journal J Cell Mol Med

Specialties Cell Biology
Molecular Biology

Date 2018 Jan 30

PMID 29377463

Citations 58

Authors

Elie Beit-Yannai

Saray Tabak

W Daniel Stamer

Affiliations

Soon will be listed here.

Abstract

Exosomes are extracellular nanovesicles that mediate a number of cellular processes, including intracellular signalling. There are many published examples of exosome-exosome dimers; however, their relevance has not been explored. Here, we propose that cells release exosomes to physically interact with incoming exosomes, forming dimers that we hypothesize attenuate incoming exosome-mediated signalling. We discuss experiments to test this hypothesis and potential relevance in health and disease.

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