Influence of Obesity on the Course of Malignant Neoplastic Disease in Patients After Pulmonary Metastasectomy

Overview

Journal In Vivo

Specialty Oncology

Date 2017 Dec 25

PMID 29275320

Citations 3

Authors

Adam Rzechonek

Piotr Blasiak

Grzegorz Pniewski

Piotr Cierpikowski

Monika Moscibrodzka

Maciej Ornat

Jedrzej Grzegrzolka

Anna Brzecka

Affiliations

Soon will be listed here.

Abstract

Background/aim: The aim of the study was to determine whether increased body mass index (BMI) in patients operated on for lung metastases influences the course of the disease.

Materials And Methods: The retrospective data of 97 patients previously operated on for different malignancies were analyzed. There were 40 obese patients (BMI >30 kg/m, mean 33.9±4.5) and 57 non-obese patients (BMI 25.8±2.7 kg/m, p<0.001). Disease-free interval (DFI), the overall survival (OS) and survival after pulmonary metastasectomy were analyzed.

Results: DFI and OS were longer in obese than in non-obese patients (82.1±83.5 months vs. 43.0±44.4, p<0.01 and 110.7±81.3 months vs. 69.9±52.9 p<0.005, respectively). Survival after pulmonary metastasectomy was 27.2±25.6 months and was longer in obese and overweight patients than in normal weight patients (20.2±18.4 months vs. 29.4±26.5, p<0.05).

Conclusion: Being obese or overweight is a favorable prognostic factor in patients after surgical resection of lung metastases of different malignancies.

Citing Articles

The Role of Obesity in Early and Long-Term Outcomes after Surgical Excision of Lung Oligometastases from Colorectal Cancer.

Londero F, Parise O, Grossi W, Morelli A, Masullo G, Bartoletti M J Clin Med. 2020; 9(11).

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Delaware's 1999-2017 Leading Causes of Death Information Illustrates Its Obesity and Obesity-Related Life-Limiting Disease Burdens.

DSouza M, Li R, Wentzien D Res Health Sci. 2019; 4(4):327-346.

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1997-2017 Leading Causes of Death Information Due to Diabetes, Neoplasms, and Diseases of the Circulatory System, Issues Cautionary Weight-Related Lesson to the US Population at Large.

DSouza M, Li R, Gannon M, Wentzien D IEEE Netw. 2019; 2019:1-6.

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