Bio-Functional Design, Application and Trends in Metallic Biomaterials

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2017 Dec 23

PMID 29271916

Citations 19

Authors

Ke Yang

Changchun Zhou

Hongsong Fan

Yujiang Fan

Qing Jiang

Ping Song

Hongyuan Fan

Yu Chen

Xingdong Zhang

Affiliations

Soon will be listed here.

Abstract

Introduction of metals as biomaterials has been known for a long time. In the early development, sufficient strength and suitable mechanical properties were the main considerations for metal implants. With the development of new generations of biomaterials, the concepts of bioactive and biodegradable materials were proposed. Biological function design is very import for metal implants in biomedical applications. Three crucial design criteria are summarized for developing metal implants: (1) mechanical properties that mimic the host tissues; (2) sufficient bioactivities to form bio-bonding between implants and surrounding tissues; and (3) a degradation rate that matches tissue regeneration and biodegradability. This article reviews the development of metal implants and their applications in biomedical engineering. Development trends and future perspectives of metallic biomaterials are also discussed.

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